Heart Rate Variability at rest and after the 6-minute walk test (6MWT) in children with cystic fibrosis
Braz. j. phys. ther. (Impr.)
;
17(5): 419-426, out. 2013. tab, graf
Article
in English
| LILACS
| ID: lil-689920
ABSTRACT
BACKGROUND:
Cystic fibrosis (CF) is a multisystem disease that affects the cardiorespiratory system and the cardiac autonomic control may be altered at rest and after a submaximal exercise.OBJECTIVE:
To assess the cardiac autonomic control by heart rate variability (HRV) analysis before and after a 6-minute walk test (6MWT).METHOD:
Thirteen children diagnosed with Cystic Fibrosis (CFG) aged 12±2.7 years (FEV1/FVC 0.83±0.11, FEV1 71.4±21 %pred) and 12 healthy children (control group-CG) aged 11.4±2.4 years (FEV1/FVC 0.91±0.12, FEV1 91.6±17.4 %pred) were included in the study. HRV was evaluated prior to and immediately after the 6MWT and the heart rate recovery assessed on the first and second minute after test.RESULTS:
Prior to exercise, CF patients presented higher values for the variables LFnu (53.2±15.0 vs. 32.8±7.9, p=0.0003) and LF/HF (1.25±0.72 vs. 0.49±0.18, p<0.006) as well as lower values of HF% (25.4±18.4 vs. 53±9.6, p=0.002) and HFnu (47.3±14.7 vs. 68.3±8.7, p0.001) when compared to CG. After the 6MWT, both groups demonstrated HRV recovery to baseline levels; however, the differences between CFG and CG were maintained for the variables LF(ms 2) (846.7±754.8 vs. 345.6±197.2, p=0.02); LF% (35.4±8.1 vs. 25.9±6.2, p=0.002); LFnu (60.0±16.3 vs. 34.9±8.7, p<0.0001); HF% (27.4±13.7 vs. 48.1±6.3, p=0.0003); HFnu (40.4±15.8 vs. 65.6±8.2, p=0.0003) and LF/HF (1.9±1.7 vs. 0.5±0.2, p=0.0001).CONCLUSIONS:
Children with cystic fibrosis exhibited predominance of sympathetic activity at rest that persisted after the 6-minute walking test when compared to the control group. .
Full text:
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Index:
LILACS (Americas)
Main subject:
Cystic Fibrosis
/
Exercise Test
Type of study:
Observational study
/
Prevalence study
/
Risk factors
Limits:
Child
/
Female
/
Humans
/
Male
Language:
English
Journal:
Braz. j. phys. ther. (Impr.)
Journal subject:
MEDICINA FISICA E REABILITACAO
Year:
2013
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal do Rio Grande do Norte/BR
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