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Falha a longo prazo no tratamento do melanoma de coróide com termoterapia transpupilar / Long-term failure after transpupillary thermotherapy for small choroidal melanomas
Pasetto, Gabriela Soncini; Freitas, Henrique Pedroso de; Colossi, Carina Graziottin; Vilela, Manuel Augusto Pereira.
  • Pasetto, Gabriela Soncini; Instituto de Oftalmologia Professor Ivo Corrêa-Meyer. Porto Alegre. BR
  • Freitas, Henrique Pedroso de; Instituto de Oftalmologia Professor Ivo Corrêa-Meyer. Porto Alegre. BR
  • Colossi, Carina Graziottin; Instituto de Oftalmologia Professor Ivo Corrêa-Meyer. Porto Alegre. BR
  • Vilela, Manuel Augusto Pereira; Universidade Federal de Pelotas. Pelotas. BR
Rev. bras. oftalmol ; 72(4): 249-252, jul.-ago. 2013. ilus, tab
Article in Portuguese | LILACS | ID: lil-690261
RESUMO

Objetivo:

Avaliar, retrospectivamente, num longo intervalo de tempo, os resultados da termoterapia transpupilar em casos selecionados do melanoma de coróide.

Métodos:

Foram identificados todos os casos com melanoma de coróide tratados com termoterapia transpupilar, como terapia única ou suplementar. Foram excluídos os casos com seguimento inferior a 60 meses, prontuários incompletos ou com o abandono do acompanhamento.

Resultados:

De um total de 18 olhos, 7 (38.9%) foram incluídos no estudo. Cinco (71,4%) pacientes foram tratados exclusivamente com termoterapia transpupilar, em 1 (14,2%) olho a crioterapia foi simultânea, 1 (14,2%) suplementou braquiterapia - placa episcleral. Três (42.8%) sofreram recorrência, 2 (28.5%) apresentaram metástases (um óbito), 2 foram enucleados. Complicações foram encontradas em 3 olhos dobras maculares em 2, hemorragia vítrea em 1. Nos olhos enucleados, não havia extensão extraescleral, porém células interesclerais foram identificadas.

Conclusão:

Termoterapia transpupilar mostra um declínio em sua eficácia e conserva os riscos de metástases em períodos mais longos de acompanhamento, sendo necessária uma definição mais exata de seu papel nos melanomas de coróide.
ABSTRACT

Objective:

To evaluate, retrospectively, in a long time interval, the results of transpupillary thermotherapy in selected cases of choroidal melanoma (CM).

Methods:

All patients with melanoma treated with transpupillary thermotherapy as sole therapy or supplement were identified. Cases with less than 60 months follow-up, incomplete records or abandonment of monitoring were excluded.

Results:

A total of 18 eyes, seven (38.9%) were included. Five (71,4%) patients were treated exclusively with transpupillary thermotherapy, in one (14,2%) eye criotherapy was used simultaneously, one (14,2%) was supplemented with brachytherapy - episcleral plate. Three (42.8%) had recurrence, two (28.5%) had metastases (one death), two eyes were enucleated. Complications were found in three eyes two with macular folds, one with vitreous hemorrhage. In the enucleated eyes, extraescleral did not occur, however intrascleral tumoral cells were identified.

Conclusion:

Transpupillary thermotherapy shows a decline in its effectiveness and retains the risk of metastases in longer periods of follow-up, requiring a more exact definition of its role in choroidal melanoma.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Brachytherapy / Choroid Neoplasms / Cryotherapy / Hyperthermia, Induced / Melanoma Type of study: Observational study / Risk factors Limits: Female / Humans Language: Portuguese Journal: Rev. bras. oftalmol Journal subject: Ophthalmology Year: 2013 Type: Article Affiliation country: Brazil Institution/Affiliation country: Instituto de Oftalmologia Professor Ivo Corrêa-Meyer/BR / Universidade Federal de Pelotas/BR

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Full text: Available Index: LILACS (Americas) Main subject: Brachytherapy / Choroid Neoplasms / Cryotherapy / Hyperthermia, Induced / Melanoma Type of study: Observational study / Risk factors Limits: Female / Humans Language: Portuguese Journal: Rev. bras. oftalmol Journal subject: Ophthalmology Year: 2013 Type: Article Affiliation country: Brazil Institution/Affiliation country: Instituto de Oftalmologia Professor Ivo Corrêa-Meyer/BR / Universidade Federal de Pelotas/BR