Functional differences ofPorphyromonas gingivalisfimbriae in determining periodontaldisease pathogenesis: a literature review / "Prevalencia de los genotipos FimA de Porphyromonas gingivalis en diferentes poblaciones mundiales: Revisión de la Literatura"

ABSTRACT

Porphyromonas gingivalisis implicated in chronic and ag-gressive periodontitis. This bacterium has numerous vi-rulence factors and one is the fimbriae, which is quite im-portant for bacterial colonization. Fimbriae are appendicesthat anchor to the bacterial wall and are comprised of theprotein fimbriline encoded by the fimA gene. Thus far, sixgenotypes have been identified, fimA I to V and Ib. Ge-notypes II and IV are associated with periodontal disea-se, while genotype I is related to gingival health. Genotypeidentification ofP. gingivalisfimA in periodontitis wouldbe important to confirm the pathogenic genotypes and toestablish risk at population level. This review is about theP. gingivalisfimA genotype prevalence worldwide. A sys-tematic search using Pubmed, Hinary, and Science Directwithin the following descriptorsPorphyromonas gingivalis,bacterial adhesion, periodontitis, fimbriae, fimA, genotipi-fication was performed to April 2011.