Hematological particularities and co-infections in injected drug users with AIDS
Braz. j. infect. dis
;
17(6): 654-656, Nov.-Dec. 2013. tab
Article
in English
| LILACS
| ID: lil-696965
ABSTRACT
HIV patients infected through injected drug use have poorer prognosis than other groups. We evaluated the hematological alterations and rates of co-infections in injected drug use patients with AIDS. Injected drug use patients were younger, predominantly of male gender, and presented lower CD4, total lymphocyte, and platelet counts, but not neutrophil count, than control group. Injected drug use patients had a higher rate of hepatitis C and mycobacteria infection. Furthermore, all injected drug use patients with hemoglobin <10.0 g dL-1 and lymphocyte <1000 µL-1 had CD4 count lower than 100 µL-1. In conclusion, HIV-infected injected drug use patients constitute a special group of patients, and hemoglobin concentration and lymphocyte count can be used as surrogate markers for disease severity.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Substance Abuse, Intravenous
/
Acquired Immunodeficiency Syndrome
/
Coinfection
Type of study:
Diagnostic study
/
Observational study
/
Prevalence study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2013
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade de São Paulo (USP)/BR
Similar
MEDLINE
...
LILACS
LIS