A short neuropsychological evaluation of patients with primary Sjogren's syndrome / Avaliacao neuropsicologica breve em pacientes com sindrome de Sjogren primaria
Arq. neuropsiquiatr
;
72(1): 38-43, 01/2014. tab
Article
in English
| LILACS
| ID: lil-697607
ABSTRACT
Objective:
To investigate cognitive deficits in patients with primary Sjögren’s syndrome (PSS).Method:
Eighteen patients with PSS, aged between 25 and 61 years, were subjected to a short neuropsychological battery and compared with 18 patients with multiple sclerosis and 18 healthy controls.Results:
The analysis of variance (ANOVA) revealed that the clinical groups had significantly worse performance than the control group on the Rey Auditory Verbal Learning Test 3; (F 2,53 =3.500, p=0.038) and 7 (F 2,53 =5.068, p=0.010). The clinical groups had elevated levels of depression on the Beck Depression Inventory (BDI); (p=0.003). The analysis of the data from the Trail Making Test B-A revealed a significant difference between the clinical and control groups (p=0.023). The analysis of covariance with BDI score as a covariate, did not change the outcome.Conclusion:
Our study revealed cognitive deficits in patients with PSS detectable by a short neuropsychological battery. .RESUMO
Objetivo:
Investigar déficits cognitivos em pacientes com síndrome de Sjögren primária (SSP) utilizando bateria neuropsicológica breve.Método:
Dezoito pacientes com SSP e idade entre 25 e 61 anos, foram submetidos a uma bateria neuropsicológica breve e os resultados comparados com 18 pacientes com esclerose múltipla e com 18 controles saudáveis.Resultados:
A análise da variância revelou que os grupos clínicos apresentaram desempenho significativamente pior que os controles ao Rey Auditory Verbal Learning Test 3 (RAVLT 3; F 2,53 =3,500, p=0,038) e RAVLT 7 (F 2,53 =5,068, p=0,010). Os grupos clínicos apresentaram índices elevados de depressão pela Beck Depression Inventor y (BDI); (F 2,53 =0.003). O desempenho no Trail Making Test B-A revelou diferença significativa entre os grupos clínicos e o grupo controle (p=0,023). A análise de covariância tomando a BDI como covariante, não revelou mudanças nos resultados.Conclusão:
Nosso estudo revelou comprometimento cognitivo em pacientes com SSP detectável por bateria neuropsicológica breve. .
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Sjogren's Syndrome
/
Cognition Disorders
/
Neuropsychological Tests
Type of study:
Diagnostic study
/
Evaluation studies
/
Observational study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Arq. neuropsiquiatr
Journal subject:
Neurology
/
Psychiatry
Year:
2014
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal do Estado do Rio de Janeiro/BR
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