Circadian rhythms in insect disease vectors
Mem. Inst. Oswaldo Cruz
;
108(supl.1): 48-58, 2013. graf
Article
in English
| LILACS
| ID: lil-697831
ABSTRACT
Organisms from bacteria to humans have evolved under predictable daily environmental cycles owing to the Earth’s rotation. This strong selection pressure has generated endogenous circadian clocks that regulate many aspects of behaviour, physiology and metabolism, anticipating and synchronising internal time-keeping to changes in the cyclical environment. In haematophagous insect vectors the circadian clock coordinates feeding activity, which is important for the dynamics of pathogen transmission. We have recently witnessed a substantial advance in molecular studies of circadian clocks in insect vector species that has consolidated behavioural data collected over many years, which provided insights into the regulation of the clock in the wild. Next generation sequencing technologies will facilitate the study of vector genomes/transcriptomes both among and within species and illuminate some of the species-specific patterns of adaptive circadian phenotypes that are observed in the field and in the laboratory. In this review we will explore these recent findings and attempt to identify potential areas for further investigation.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Circadian Rhythm
/
Drosophila melanogaster
/
Period Circadian Proteins
/
Insect Vectors
/
Culicidae
Type of study:
Prognostic study
Limits:
Animals
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2013
Type:
Article
Affiliation country:
Switzerland
Institution/Affiliation country:
Ecole Polytechnique Federale de Lausanne/CH
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