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The effects of a diet formulation with oats, soybeans, and flax on lipid profiles and uricemia in patients with AIDS and dyslipidemia
Ferreira, Rosangela dos Santos; Cassaro, Daiane Colman; Domingos, Hamilton; Pontes, Elenir Rose Jardim Cury; Aiko, Priscila Hiane; Meira, Junia Elisa Carvalho de.
  • Ferreira, Rosangela dos Santos; Universidade Federal do Mato Grosso do Sul. Programa de Pos-Graduacao em Saude e Desenvolvimento na Regiao Centro-Oeste. Campo Grande. BR
  • Cassaro, Daiane Colman; Universidade Federal do Mato Grosso do Sul. Programa de Pos-Graduacao em Saude e Desenvolvimento na Regiao Centro-Oeste. Campo Grande. BR
  • Domingos, Hamilton; Universidade Federal do Mato Grosso do Sul. Programa de Pos-Graduacao em Saude e Desenvolvimento na Regiao Centro-Oeste. Campo Grande. BR
  • Pontes, Elenir Rose Jardim Cury; Universidade Federal do Mato Grosso do Sul. Programa de Pos-Graduacao em Saude e Desenvolvimento na Regiao Centro-Oeste. Campo Grande. BR
  • Aiko, Priscila Hiane; Universidade Federal do Mato Grosso do Sul. Programa de Pos-Graduacao em Saude e Desenvolvimento na Regiao Centro-Oeste. Campo Grande. BR
  • Meira, Junia Elisa Carvalho de; Universidade Federal do Mato Grosso do Sul. Programa de Pos-Graduacao em Saude e Desenvolvimento na Regiao Centro-Oeste. Campo Grande. BR
Rev. Soc. Bras. Med. Trop ; 46(6): 691-697, Nov-Dec/2013. tab
Article in English | LILACS | ID: lil-698058
ABSTRACT
Introduction Although the initiation of highly active antiretroviral therapy (HAART) is accompanied by an attenuation of viral load, metabolic disorders characterized by hyperglycemia, dyslipidemia, and lipodystrophy are often observed in patients under this treatment. Certain foods, such as oat bran, soy protein, and flaxseed, have been shown to improve a patient's lipid profile despite possible increases in uricemia. Thus, a bioactive compound was formulated using these foods to help patients with HIV/AIDS control metabolic disorders resulting from HAART. Methods An uncontrolled before and after study was performed. The total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides, and uric acid before and after 3 months of consuming the formulation were compared in patients. The compound was formulated such that 40g (the recommended daily intake) contained approximately 10g of flaxseed, 20g of oat bran, and 10g of textured soy protein. Results The study population consisted of 139 patients, 31 of whom were included in the final analysis. There were no significant variations between the laboratory results obtained before and after consumption of the compound. Conclusions The regular consumption of the formulation together with individualized dietary guidance did not reduce lipid levels and did not contribute to an increase in uricemia in the study group. However, new studies with higher doses of the foods that compose the formulation should be encouraged to investigate whether these foods can positively influence the lipid profiles of these patients. .
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Full text: Available Index: LILACS (Americas) Main subject: Uric Acid / Food, Formulated / Acquired Immunodeficiency Syndrome / Antiretroviral Therapy, Highly Active / Dyslipidemias / Lipids Type of study: Practice guideline Limits: Adult / Aged / Aged80 / Female / Humans / Male Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2013 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Mato Grosso do Sul/BR

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Full text: Available Index: LILACS (Americas) Main subject: Uric Acid / Food, Formulated / Acquired Immunodeficiency Syndrome / Antiretroviral Therapy, Highly Active / Dyslipidemias / Lipids Type of study: Practice guideline Limits: Adult / Aged / Aged80 / Female / Humans / Male Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2013 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Mato Grosso do Sul/BR