In vitro evaluation of cytotoxicity of different brands of artificial teeth / Avaliação in vitro da citotoxicidade de dentes artificiais de diferentes marcas comerciais

ABSTRACT

Aim: The present study aimed to evaluate the cytotoxicity of different brands of stock acrylic teeth against fibroblast cells. Materials and Methods: For this experiment, the cell lineage used was the L929 from the American Type Culture Collection (ATCC, Rockville, MD, USA). The brands of stock teeth tested included Artplus, Biolux, Biotone, Pop Dent, Vipi Dent, Orthosit Ivoclar, Biocler, and Trilux. Each group was placed in contact with the fibroblast cells for the periods of 24, 48, 72, and 168 hours. Control cells, as well asnegative and positive controls, were used to compare the extremes. Results: The results showed cytotoxicity for all the groups tested in the time periods of 24, 48, and 72 hours during the experiment, which occurred in theOrthosit Ivoclar and Trilux groups even after the experiment had been conducted for 168 hours. Conclusion:The researched acrylic teeth developed cytotoxicity against the cells in vitro during the time periods of 24, 48, and 72 hours, while Ivoclar Vivodent and Trilux brands of teeth developed cytotoxicity against the tested cellsduring the time period of 168 hours.