Alterations of the gastric stump and not resected stomach mucosa after truncal vagotomy in rats
Acta cir. bras
;
29(2): 99-103, 02/2014. graf
Article
in English
| LILACS
| ID: lil-702521
ABSTRACT
To evaluate morphological changes of the gastric stump and not resected stomach mucosa after the completion of truncal vagotomy. METHODS:
Eighty male Wistar rats were divided into four groups CT, TV, RY and RYTV. In CT group, abdominal viscera were manipulated and the abdominal cavity was closed, in TV vagal trunks were isolated and sectioned, in RY a partial Roux-en-Y gastrectomy was performed and in RYTV the vagal trunks were sectioned and a partial Roux-en-Y gastrectomy was performed. At the 54th week after surgery, the rats were euthanized. The findings were submitted to histological analyses.RESULTS:
None macroscopic or histological alterations in groups TV and CT was observed. Specimens from RY and RYTV groups did not show alterations in the gastric stump mucosa. At the jejunal side of the gastroenterostomy we found shallow ulcerative lesions always single, well-defined and with variable diameter 3 to 6 mm, six times in the RY group and none in the RYTV group (RY>RYTV, p=0.008). Neoplastic or preneoplastic lesions were not diagnosed in all groups.CONCLUSION:
Truncal vagotomy is a safe and non-carcinogenic method in not resected and partially resected stomach.
Full text:
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Index:
LILACS (Americas)
Main subject:
Stomach
/
Vagotomy
/
Gastric Mucosa
Limits:
Animals
Language:
English
Journal:
Acta cir. bras
Journal subject:
General Surgery
/
Procedimentos Cir£rgicos Operat¢rios
Year:
2014
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Estadual Paulista/BR
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