Reticulocyte maturity indices in iron deficiency anemia
Rev. bras. hematol. hemoter
;
36(1): 25-28, Jan-Feb/2014. tab
Article
in English
| LILACS
| ID: lil-703708
ABSTRACT
Objective:
The aim of this study was to analyze the reticulocyte maturity indices (low, medium, and high fluorescence ratios) in iron deficient 1- to 6-year-old children, and identify the prevalence of iron deficiency anemia in this population.Methods:
The present study included 39 subjects, divided into two groups control subjects (n = 33), and subjects with iron deficiency anemia (n = 6). The results were analyzed by Student's t-test for comparison of means. Differences were considered significant when two-tailed p-value < 0.05.Results:
Subjects with iron deficiency anemia presented increases in the proportion of mean (10.3 ± 4.7% vs. 6.0 ± 3.4%; p-value = 0.003), and high fluorescence reticulocytes (2.3 ± 0.87% vs. 0.9 ± 0.9%; p-value = 0.03) compared to the control group. The prevalence of anemia in this population was 15% (n = 6).Conclusion:
The indices related to immaturity of reticulocytes are higher in the presence of iron deficiency, thus demonstrating a deficiency in the raw material to form hemoglobin and are, therefore, possible early markers of iron deficiency and anemia. We emphasize the need to standardize these indices for use in clinical practice and lab test results. .
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Reticulocytes
/
Child
/
Anemia, Iron-Deficiency
Type of study:
Prognostic study
/
Risk factors
Limits:
Child, preschool
/
Humans
/
Infant
Language:
English
Journal:
Rev. bras. hematol. hemoter
Journal subject:
Hematology
Year:
2014
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Homocentro Regional de Pelotas/BR
/
Laboratório de Análises Clínicas J&R/BR
/
Universidade Luterana do Brasil/BR
/
Universidade de Santa Cruz do Sul/BR
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