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Hypoxia among patients on the liver-transplant waiting list / Hipoxia entre os pacientes na lista de espera para transplante de figado
NACIF, Lucas Souto; ANDRAUS, Wellington; SARTORI, Kathryn; BENITES, Carlos Marlon; SANTOS, Vinicius Rocha; ROCHA-FILHO, Joel Avancini; D'ALBUQUERQUE, Luiz Carneiro.
Affiliation
  • NACIF, Lucas Souto; University of Sao Paulo. School of Medicine. Department of Gastroenterology. Sao Paulo. BR
  • ANDRAUS, Wellington; University of Sao Paulo. School of Medicine. Department of Gastroenterology. Sao Paulo. BR
  • SARTORI, Kathryn; University of Sao Paulo. School of Medicine. Department of Gastroenterology. Sao Paulo. BR
  • BENITES, Carlos Marlon; University of Sao Paulo. School of Medicine. Department of Gastroenterology. Sao Paulo. BR
  • SANTOS, Vinicius Rocha; University of Sao Paulo. School of Medicine. Department of Gastroenterology. Sao Paulo. BR
  • ROCHA-FILHO, Joel Avancini; University of Sao Paulo. School of Medicine. Department of Gastroenterology. Sao Paulo. BR
  • D'ALBUQUERQUE, Luiz Carneiro; University of Sao Paulo. School of Medicine. Department of Gastroenterology. Sao Paulo. BR
ABCD (São Paulo, Impr.) ; 27(1): 56-58, Jan-Mar/2014. graf
Article in En | LILACS | ID: lil-703978
Responsible library: BR1.1
ABSTRACT

Background:

Hepatopulmonary syndrome is formed by a triad of liver disease, intrapulmonary vascular dilatation and changes in blood gases. This condition is present in 4-32% of patients with cirrhosis.

Aim:

To analyze the blood gas changes data of patients in liver-transplant waiting list.

Method:

Clinical data of 279 patients in liver transplantation waiting list in May 2013 were studied. Overall patient was analyzed by the demographic aspects, laboratorial and image findings on exams that determine lung disease (hypoxemia) in these cirrhotic patients. The mean values and standard deviations were used to examine normally distributed variables.

Results:

There was a high prevalence of male patients (68%); the mean age was 51(±5,89) years, and the predominant reason for listing was hepatitis C cirrhosis. The MELD score mean was 16±5,89, without prioritization or special situation. The most common blood type was O in 129 cases (46%) and the mean of body max index was 25,94±4,58. Regarding arterial blood gas tests was observed 214 patients with PaO2 <90 mmHg, 80 with PaO2 <80 mmHg and 39 with PaO2 <50 mmHg. In relation to O2 saturation, 50 patients had <90%, 33 <80% and 10 <50%.

Conclusion:

Was observed a high rate of hypoxemia in patients on waiting list liver transplant. Due to the high severity and morbidity, is suggested better monitoring and therapeutic support to hypoxemic patients on liver transplant waiting list. .
RESUMO
Racional A síndrome hepatopulmonar é formada por tríade clínica com doença do fígado, dilatação vascular intrapulmonar e alterações nos gases sanguíneos. Esta condição está presente em 4-32% dos pacientes com cirrose.

Objetivo:

Analisar as alterações gasométricas nos pacientes em lista de espera de transplante de fígado.

Método:

Foram estudados dados clínicos de 279 pacientes na lista de espera para transplante hepático em maio de 2013. Foram analisados aspectos demográficos, gasometria arterial e achados de imagem que determinam a doença pulmonar (hipoxemia) nestes pacientes cirróticos. Os valores médios e desvios-padrão foram utilizados para examinar as variáveis ​​normalmente distribuídas.

Resultados:

Houve alta prevalência de homens (68%); a idade média foi de 51 (±5,89) anos; e a razão predominante para listar para o transplante foi cirrose pelo vírus C. O MELD médio foi de 16±5,89, sem priorização ou situação especial. O tipo de sangue mais comum foi O, 129 casos (46%) e a média do índice de massa corporal foi 25,94±4,58. Com relação aos exames de gasometria arterial, observou-se 214 pacientes com PaO2 <90 mmHg, 80 com PaO2 <80 mmHg e 39 com PaO2 <50 mmHg, e em relação à saturação de O2, 50 pacientes <90%, 33 pacientes <80% e 10 pacientes <50%.

Conclusão:

Observou-se alta taxa de hipoxemia nos pacientes em lista de transplante de fígado; devido à elevada gravidade e morbidade, sugere-se melhor seguimento e suporte terapêutico aos doentes hipoxêmicos na lista de espera para o transplante de fígado. .
Subject(s)
Key words

Full text: 1 Index: LILACS Main subject: Liver Transplantation / Hepatopulmonary Syndrome / Hypoxia Type of study: Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: ABCD (São Paulo, Impr.) Journal subject: CIRURGIA GERAL / GASTROENTEROLOGIA / Procedimentos Cir£rgicos Operat¢rios / Sistema Digest¢rio Year: 2014 Type: Article

Full text: 1 Index: LILACS Main subject: Liver Transplantation / Hepatopulmonary Syndrome / Hypoxia Type of study: Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: ABCD (São Paulo, Impr.) Journal subject: CIRURGIA GERAL / GASTROENTEROLOGIA / Procedimentos Cir£rgicos Operat¢rios / Sistema Digest¢rio Year: 2014 Type: Article