Your browser doesn't support javascript.
loading
Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae)
Cardoso, Claudia Andréa Lima; Coelho, Roberta Gomes; Honda, Neli Kika; Pott, Arnildo; Pavan, Fernando Rogério; Leite, Clarice Queico Fujimura.
  • Cardoso, Claudia Andréa Lima; State University of Mato Grosso do Sul. Course of Chemistry. Dourados. BR
  • Coelho, Roberta Gomes; State University of Mato Grosso do Sul. Course of Chemistry. Dourados. BR
  • Honda, Neli Kika; State University of Mato Grosso do Sul. Course of Chemistry. Dourados. BR
  • Pott, Arnildo; State University of Mato Grosso do Sul. Course of Chemistry. Dourados. BR
  • Pavan, Fernando Rogério; State University of Mato Grosso do Sul. Course of Chemistry. Dourados. BR
  • Leite, Clarice Queico Fujimura; State University of Mato Grosso do Sul. Course of Chemistry. Dourados. BR
Braz. j. pharm. sci ; 49(4): 775-782, Oct.-Dec. 2013. ilus, tab
Article in English | LILACS | ID: lil-704109
ABSTRACT
Serjania erecta Radlk.(Sapindaceae) is a medicinal plant traditionally used in Brazil. We assayed the ethanolic extract of leaves and roots against seven microorganisms. The REMA (Resazurin Microtiter Assay) assay was used to measure the biological activity in vitro against Mycobacterium tuberculosis and our results showed moderate activity of the ethanolic extract. On the other hand S. aureus, P. aeruginosa, S. setubal, C. albicans, S. cerevisiae and E. coli revealed that the leaves and roots of S. erecta inhibited the growth of all microorganisms. The ethanolic extracts of leaves and roots showed low values of antioxidant activities. The ethanolic extracts of leaves and roots were analyzed by chromatographic and spectrometric methods. (-)-Epicatechin, kaempferol aglycone and five glycoside derivates were isolated kaempferol-3-O-α-L-rhamnopyranoside, kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside from the roots and kaempferol, kaempferol 3,7-di-O-α-L-rhamnopyranoside, vitexin, isovitexin and (-)-epicatechin in the leaves. This is the first chemical study reported in the literature about this specie.
RESUMO
Serjania erecta Radlk. (Sapindaceae) é uma planta medicinal utilizada no Brasil. Analisamos o extrato etanólico de folhas e raízes para sete microorganismos. O REMA (Ensaio de Microtitulação Resazurina) foi utilizado para medir a atividade biológica in vitro contra o Mycobacterium tuberculosis e nossos resultados mostraram atividade moderada do extrato etanólico. Por outro lado, ensaios com S. aureus, P. aeruginosa, S. setubal, C. albicans, S. cerevisiae e E. coli revelaram que as folhas e raízes de S. erecta inibiram crescimento em todos os microorganismos. Os extratos etanólicos de folhas e raízes apresentaram valores baixos de atividade antioxidante. Os extratos etanólicos de folhas e raízes foram analisados por métodos cromatográficos e espectroscópicos. (-)-Epicatequina, canferol aglicona e cinco derivados glicosídicos foram isolados canferol -3-O-α-L-ramnopiranosídeo, canferol-3-O-α-L-ramnopiranosil-(1→6)-β-D-glucopiranosídeo a partir das raízes e canferol, canferol 3,7-di-O-α-L-ramnopiranosídeo, vitexina, isovitexina e (-) epicatequina nas folhas. Este é o primeiro estudo químico na literatura sobre esta espécie.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Phenolic Compounds / Anti-Infective Agents / Anti-Bacterial Agents / Antioxidants Language: English Journal: Braz. j. pharm. sci Year: 2013 Type: Article Affiliation country: Brazil Institution/Affiliation country: State University of Mato Grosso do Sul/BR

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Index: LILACS (Americas) Main subject: Phenolic Compounds / Anti-Infective Agents / Anti-Bacterial Agents / Antioxidants Language: English Journal: Braz. j. pharm. sci Year: 2013 Type: Article Affiliation country: Brazil Institution/Affiliation country: State University of Mato Grosso do Sul/BR