Analysis of the effect of renal excretory system cooling during thermal radiofrequency ablation in an animal model
Int. braz. j. urol
;
40(1): 93-99, Jan-Feb/2014. tab, graf
Article
in English
| LILACS
| ID: lil-704177
ABSTRACT
Objective:
Analysis of renal excretory system integrity and efficacy of radiofrequency ablation with and without irrigation with saline at 2 o C (SF2). Materials andMethods:
The median third of sixteen kidneys were submitted to radiofrequency (exposition of 1 cm) controlled by intra-surgical ultrasound, with eight minutes cycles and median temperature of 90 o C in eight female pigs. One excretory renal system was cooled with SF2, at a 30ml/min rate, and the other kidney was not. After 14 days of post-operatory, the biggest diameters of the lesions and the radiological aspects of the excretory system were compared by bilateral ascending pyelogram and the animals were sacrificed in order to perform histological analysis.Results:
There were no significant differences between the diameters of the kidney lesions whether or not exposed to cooling of the excretory system. Median diameter of the cooled kidneys and not cooled kidneys were respectively (in mm) anteroposterior 11.46 vs. 12.5 (p = 0.23); longitudinal 17.94 vs. 18.84 (p = 0.62); depth 11.38 vs. 12.25 (p = 0.47). There was no lesion of the excretory system or signs of leakage of contrast media or hydronephrosis at ascending pyelogram.Conclusion:
Cooling of excretory system during radiofrequency ablation does not significantly alter generated coagulation necrosis or affect the integrity of the excretory system in the studied model. .
Full text:
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Index:
LILACS (Americas)
Main subject:
Saline Solution, Hypertonic
/
Catheter Ablation
/
Cold Temperature
/
Models, Animal
/
Kidney
Type of study:
Prognostic study
Limits:
Animals
Language:
English
Journal:
Int. braz. j. urol
Journal subject:
Urology
Year:
2014
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Pontifical Catholic University of Campinas/BR
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