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Analysis of oxybutynin treatment for hyperhidrosis in patients aged over 40 years / Análise do tratamento de hiperidrose com oxibutinina em pacientes com mais de 40 anos
Wolosker, Nelson; Krutman, Mariana; Teivelis, Marcelo Passos; Paula, Rafael Pessanha de; Kauffman, Paulo; Campos, Jose Ribas Milanez de; Puech-Leão, Pedro.
  • Wolosker, Nelson; Hospital Israelita Albert Einstein. São Paulo. BR
  • Krutman, Mariana; Hospital Israelita Albert Einstein. São Paulo. BR
  • Teivelis, Marcelo Passos; Hospital Israelita Albert Einstein. São Paulo. BR
  • Paula, Rafael Pessanha de; Hospital Israelita Albert Einstein. São Paulo. BR
  • Kauffman, Paulo; Hospital Israelita Albert Einstein. São Paulo. BR
  • Campos, Jose Ribas Milanez de; Hospital Israelita Albert Einstein. São Paulo. BR
  • Puech-Leão, Pedro; Hospital Israelita Albert Einstein. São Paulo. BR
Einstein (Säo Paulo) ; 12(1): 42-47, Jan-Mar/2014. tab
Article in English | LILACS | ID: lil-705795
ABSTRACT

Objective:

Our aim was to analyze the effectiveness of oxybutynin for hyperhidrosis treatment in patients over 40 years.

Methods:

Eighty-seven patients aged over 40 years were divided into two groups. One group consisted of 48 (55.2%) patients aged between 40 and 49 years, and another was composed of 39 (44.8%) patients aged over 50 years (50 to 74 years). A comparative analysis of Quality of Life and level of hyperhidrosis between the groups was carried out 6 weeks after a protocol treatment with oxybutynin. A validated clinical questionnaire was used for evaluation.

Results:

In the younger age group, 75% of patients referred a “partial” or “great” improvement in level of hyperhidrosis after treatment. This number was particularly impressive in patients over 50 years, in which 87.2% of the cases demonstrated similar levels of improvement. Over 77% of patients in both groups demonstrated improvement in Quality of Life. Excellent outcomes were observed in older patients, in which 87.1% of patients presented “slightly better” (41%) or “much better” (46.1%) improvement.

Conclusion:

Patients aged over 40 years with hyperhidrosis presented excellent results after oxybutynin treatment. These outcomes were particularly impressive in the age group over 50 years, in which most patients had significant improvement in Quality of Life and in level of hyperhidrosis. .
RESUMO

Objetivo:

Analisar a efetividade da oxibutinina para tratamento da hiperidrose em pacientes com mais de 40 anos.

Métodos:

Oitenta e sete pacientes com idade superior a 40 anos foram divididos em dois grupos o primeiro com 48 pacientes (55,2%), com idades entre 40 e 49 anos. O segundo com 39 pacientes (44,8%), com mais de 50 anos (intervalo 50 a 74 anos). Uma análise comparativa da Qualidade de Vida e do nível de hiperidrose entre os grupos foi realizada 6 semanas após o início do tratamento com oxibutinina. Para isso, foi utilizado um questionário validado para Qualidade de Vida.

Resultados:

No grupo mais jovem, 75% dos pacientes referiram melhora “parcial” ou “ótima” no nível de hiperidrose após o tratamento. Esse número foi particularmente impressionante em pacientes acima de 50 anos, sendo que 87,2% apresentaram níveis similares de melhora. Mais de 77% dos pacientes, em ambos os grupos, demonstraram melhora na Qualidade de Vida. Desfechos excelentes foram observados em pacientes mais idosos, dentre os quais 87,1% dos pacientes apresentaram melhora “pouco melhor” (41%) ou “muito melhor” (46,1%).

Conclusão:

Os pacientes acima de 40 anos com hiperidrose tiveram excelentes resultados com o tratamento com oxibutinina. Esses desfechos foram particularmente importantes nos pacientes com mais de 50 anos, nos quais a maioria apresentou melhora da Qualidade de Vida e da hiperidrose. .
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Quality of Life / Muscarinic Antagonists / Hyperhidrosis / Mandelic Acids Type of study: Practice guideline / Observational study Limits: Adult / Aged / Female / Humans / Male Language: English Journal: Einstein (Säo Paulo) Journal subject: Medicine Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: Hospital Israelita Albert Einstein/BR

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Full text: Available Index: LILACS (Americas) Main subject: Quality of Life / Muscarinic Antagonists / Hyperhidrosis / Mandelic Acids Type of study: Practice guideline / Observational study Limits: Adult / Aged / Female / Humans / Male Language: English Journal: Einstein (Säo Paulo) Journal subject: Medicine Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: Hospital Israelita Albert Einstein/BR