Effects of nonsteroidal anti-inflammatorydrug on prevalence of helicobacter like organisms in gastric mucosa of thoroughbreds horses
Arch. venez. farmacol. ter
;
30(3): 51-54, jul.-sept. 2011. ilus
Article
in English
| LILACS
| ID: lil-706174
ABSTRACT
The aim of this study was describe effects of NonsteroidalAnti-inflammatory drug on prevalence of Helicobacter LikeOrganisms in gastric mucosa of Thoroughbreds horses. Werestudied 54 Thoroughbred horses in the national race TrackLa Rinconada Caracas-Venezuela. All equine were treatedby seven days with phenylbutazone at an intravenous doseof 4.4 mg/kg. All horses presented Equine gastric ulcer syndromeacute superficial gastritis (25/54), chronic gastritis witherosion focal (16/54), chronic gastritis with erosion focal andulcers (14/54) in the gastric in both regions mucosa squamousregion and glandular regions (fundus). Helicobacter Like Organismsinfection in the stomach was confirmed by Warthin-Starry (38/54). Gastric mucosa revealed numerous spiralshapedbacteria morphologically resembling Helicobacter LikeOrganisms in squamous regions, margo plicatus (20/38) andnumerous spiral-shaped bacteria in fundic glands (18/54). Inconclusion, we detected high presence of Helicobacter LikeOrganisms in the gastric mucosa of Thoroughbred horsestreatment with phenylbutazone.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Helicobacter Infections
/
Gastritis
/
Horse Diseases
/
Anti-Inflammatory Agents
Type of study:
Evaluation studies
/
Prevalence study
/
Risk factors
Limits:
Animals
Language:
English
Journal:
Arch. venez. farmacol. ter
Journal subject:
Pharmacology
/
Therapeutics
Year:
2011
Type:
Article
Affiliation country:
Venezuela
Institution/Affiliation country:
Universidad Central de Venezuela Núcleo Aragua/VE
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