Chronic ethanol ingestion selectively affects memory modulation in rats
Braz. j. med. biol. res
;
22(3): 403-6, 1989. tab
Article
in English
| LILACS
| ID: lil-70702
ABSTRACT
Post-training treatment alters memory by different mechanisms. Naloxone enhances memory by antagonism of endogenous ß-endorphin-induced state dependency. Epinephrine facilitates consolidation at low doses and generates state dependency at high doses. Exposure to a session of tones causes retroactive interference through a cognitive effect. The present data show that chronic ethanol ingestion, in rats, inhibited the post-training effect of naloxone and of a high dose of epinephrine on the retention of an inhibitory avoidance task but did not inhibit retrograde interference by a session of tones or retrograde facilitation by a low dose of epinephrine. Therefore, ethanol appers to selectively affect post-training influences related to state dependency
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Index:
LILACS (Americas)
Main subject:
Avoidance Learning
/
Ethanol
/
Drinking
/
Memory
Limits:
Animals
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
1989
Type:
Article
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