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Oxygen desaturation during the six-minute walk test in COPD patients / Análise da dessaturação de oxigênio durante o teste de caminhada de seis minutos em pacientes com DPOC
Moreira, Maria Ângela Fontoura; Medeiros, Gabriel Arriola de; Boeno, Francesco Pinto; Sanches, Paulo Roberto Stefani; Silva Júnior, Danton Pereira da; Müller, André Frotta.
  • Moreira, Maria Ângela Fontoura; Pulmonary Physiology Clinic. Department of Pulmonology. Porto Alegre. BR
  • Medeiros, Gabriel Arriola de; Pulmonary Physiology Clinic. Department of Pulmonology. Porto Alegre. BR
  • Boeno, Francesco Pinto; Pulmonary Physiology Clinic. Department of Pulmonology. Porto Alegre. BR
  • Sanches, Paulo Roberto Stefani; Pulmonary Physiology Clinic. Department of Pulmonology. Porto Alegre. BR
  • Silva Júnior, Danton Pereira da; Pulmonary Physiology Clinic. Department of Pulmonology. Porto Alegre. BR
  • Müller, André Frotta; Pulmonary Physiology Clinic. Department of Pulmonology. Porto Alegre. BR
J. bras. pneumol ; 40(3): 222-228, May-Jun/2014. tab, graf
Article in English | LILACS | ID: lil-714687
ABSTRACT

Objective:

To evaluate the behavior of oxygen saturation curves throughout the six-minute walk test (6MWT) in patients with COPD.

Methods:

We included 85 patients, all of whom underwent spirometry and were classified as having moderate COPD (modCOPD, n = 30) or severe COPD (sevCOPD, n = 55). All of the patients performed a 6MWT, in a 27-m corridor with continuous SpO2 and HR monitoring by telemetry. We studied the SpO2 curves in order to determine the time to a 4% decrease in SpO2, the time to the minimum SpO2 (Tmin), and the post-6MWT time to return to the initial SpO2, the last designated recovery time (RT). For each of those curves, we calculated the slope.

Results:

The mean age in the modCOPD and sevCOPD groups was 66 ± 10 years and 62 ± 11 years, respectively. At baseline, SpO2 was > 94% in all of the patients; none received supplemental oxygen during the 6MWT; and none of the tests were interrupted. The six-minute walk distance did not differ significantly between the groups. The SpO2 values were lowest in the sevCOPD group. There was no difference between the groups regarding RT. In 71% and 63% of the sevCOPD and modCOPD group patients, respectively, a ≥ 4% decrease in SpO2 occurred within the first minute. We found that FEV1% correlated significantly with the ΔSpO2 (r = −0.398; p < 0.001), Tmin (r = −0.449; p < 0.001), and minimum SpO2 (r = 0.356; p < 0.005).

Conclusions:

In the sevCOPD group, in comparison with the modCOPD group, SpO2 was lower and the Tmin was greater, suggesting a worse prognosis in the former. .
RESUMO

Objetivo:

Avaliar o comportamento da curva de saturação de oxigênio durante o teste de caminhada de seis minutos (TC6) em pacientes com DPOC.

Métodos:

Incluímos 85 pacientes e todos realizaram espirometria, sendo classificados como portadores de DPOC moderada (DPOCm, n = 30) ou grave (DPOCg, n = 55). Todos os pacientes realizaram TC6 em um corredor de 27 m com monitoramento contínuo da SpO2 e FC por telemetria. A partir das curvas de SpO2, foram analisados os tempos para atingir a queda de 4% da SpO2, para atingir a SpO2 mínima (Tmin) e para a recuperação da SpO2 após o TC6 (TR). Foram calculadas as inclinações dessas curvas.

Resultados:

A média de idade nos grupos DPOCm e DPOCg foi de 62 ± 11 anos e 66 ± 10 anos, respectivamente. Todos os pacientes iniciaram o teste com SpO2 > 94%, nenhum recebeu suplementação de oxigênio durante o TC6, e não houve interrupções. A distância percorrida no TC6 não apresentou diferença significativa entre os grupos. Os menores valores da SpO2 ocorreram no grupo DPOCg. Não houve diferença no TR entre os grupos, e 71% e 63% dos pacientes nos grupos DPOCg e DPOCm, respectivamente, apresentaram queda de SpO2 ≥ 4% até o primeiro minuto. O VEF1% apresentou correlações significativas com ΔSpO2 (r = −0,398; p < 0,001), Tmin (r = −0,449; p < 0,001) e SpO2 mínima (r = 0,356; p < 0,005).

Conclusões:

As curvas dos pacientes do grupo DPOCg em relação às do grupo DPOCm apresentaram valores menores de SpO2 e maior Tmin, sugerindo um pior prognóstico nos primeiros. .
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Oxygen Consumption / Walking / Pulmonary Disease, Chronic Obstructive Limits: Aged / Female / Humans / Male Language: English Journal: J. bras. pneumol Journal subject: Pulmonary Disease (Specialty) Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: Pulmonary Physiology Clinic/BR

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Full text: Available Index: LILACS (Americas) Main subject: Oxygen Consumption / Walking / Pulmonary Disease, Chronic Obstructive Limits: Aged / Female / Humans / Male Language: English Journal: J. bras. pneumol Journal subject: Pulmonary Disease (Specialty) Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: Pulmonary Physiology Clinic/BR