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Case for diagnosis
Maquiné, Gustavo Ávila; Maroja, Maria de Fátima; Mesquita, Cristina Rabello; Sousa, Petra Pereira de; Morais, Patrícia Motta de; Talhari, Carolina.
  • Maquiné, Gustavo Ávila; Alfredo da Matta Foundation. Manaus. BR
  • Maroja, Maria de Fátima; Alfredo da Matta Foundation. Manaus. BR
  • Mesquita, Cristina Rabello; Alfredo da Matta Foundation. Manaus. BR
  • Sousa, Petra Pereira de; Alfredo da Matta Foundation. Manaus. BR
  • Morais, Patrícia Motta de; Alfredo da Matta Foundation. Manaus. BR
  • Talhari, Carolina; Alfredo da Matta Foundation. Manaus. BR
An. bras. dermatol ; 89(4): 675-676, Jul-Aug/2014. graf
Article in English | LILACS | ID: lil-715529
ABSTRACT
We report the case of a 81-year-old female patient who had a two-year history of violet-colored erythematous tumors on both legs. Histopathological and immunohistochemical examinations confirmed the diagnosis of primary cutaneous large B-cell lymphoma, leg type. This rare, cutaneous lymphoma affects predominantly elderly females. Clinically, patients present with tumoral lesions on one or both legs (worst prognosis). Diagnosis is based on clinical, histopathological and immunohistochemical findings. The strong expression of BCL2, BCL6, MUM-1 and CD20, and the positivity for Ki67 antigen confirm the diagnosis. R-CHOP chemotherapy regimen (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone) is the most widely accepted treatment.
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Full text: Available Index: LILACS (Americas) Main subject: Skin Neoplasms / Lymphoma, B-Cell Type of study: Diagnostic study / Prognostic study Limits: Aged / Aged80 / Female / Humans Language: English Journal: An. bras. dermatol Journal subject: Dermatology Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: Alfredo da Matta Foundation/BR

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Full text: Available Index: LILACS (Americas) Main subject: Skin Neoplasms / Lymphoma, B-Cell Type of study: Diagnostic study / Prognostic study Limits: Aged / Aged80 / Female / Humans Language: English Journal: An. bras. dermatol Journal subject: Dermatology Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: Alfredo da Matta Foundation/BR