Case for diagnosis
An. bras. dermatol
;
89(4): 675-676, Jul-Aug/2014. graf
Article
in English
| LILACS
| ID: lil-715529
ABSTRACT
We report the case of a 81-year-old female patient who had a two-year history of violet-colored erythematous tumors on both legs. Histopathological and immunohistochemical examinations confirmed the diagnosis of primary cutaneous large B-cell lymphoma, leg type. This rare, cutaneous lymphoma affects predominantly elderly females. Clinically, patients present with tumoral lesions on one or both legs (worst prognosis). Diagnosis is based on clinical, histopathological and immunohistochemical findings. The strong expression of BCL2, BCL6, MUM-1 and CD20, and the positivity for Ki67 antigen confirm the diagnosis. R-CHOP chemotherapy regimen (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone) is the most widely accepted treatment.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Skin Neoplasms
/
Lymphoma, B-Cell
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Aged
/
Aged80
/
Female
/
Humans
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2014
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Alfredo da Matta Foundation/BR
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