Comparative study between homeopathy and nimesulide on the prevention of bone resorption in experimental periodontitis in rats / Estudo Comparativo entre Homeopatia e Nimesulida na Prevenção da Reabsorção Óssea em Periodontite Experimental em Ratos
Rev. Fac. Odontol. Porto Alegre
;
51(2): 5-8, maio-ago. 2010. ilus
Article
in English
| LILACS, BBO
| ID: lil-719557
ABSTRACT
Periodontitis is a chronic disease characterized by bone loss and inflammatory changes. We studied the effect of a homeopathic agent (Mercúrios Corrosivos 6 CH) and a non-steroidal anti-inflammatory drug (nimesulide) on the alveolar bone loss progression in experimentally induced periodontitis in rats. Sixty (60) Wistar rats were separated into group 1 (homeopathy), group 2 (nimesulide) and group 3 (saline solution). Silk ligatures were placed at the gingival margin level of the lower right first molar of all rats. Alveolar bone loss was evaluated by light microscopic analysis and analyzed using software Image J. The results were submitted to the analysis of variance (ANOVA) and Tukeys posttest (p<0.05). The analysis revealed that there was a higher bone loss in diseased sites as compared with healthy sites. A significant reduction in the alveolar bone resorption was observed in group 2 (nimesulide) as compared with group 1 (homeopathy) 7 days after the induction of periodontitis. Our data provided evidence that homeopathy does not decrease alveolar bone loss as opposed to nimesulide in experimentally induced periodontitis.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Periodontitis
/
Sulfonamides
/
Alveolar Bone Loss
/
Homeopathy
Limits:
Animals
Language:
English
Journal:
Rev. Fac. Odontol. Porto Alegre
Journal subject:
Dentistry
Year:
2010
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal de Alfenas/BR
/
Universidade de São Paulo/BR
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