The Plasmodium bottleneck: malaria parasite losses in the mosquito vector
Mem. Inst. Oswaldo Cruz
;
109(5): 644-661, 19/08/2014. graf
Article
in English
| LILACS
| ID: lil-720429
ABSTRACT
Nearly one million people are killed every year by the malaria parasite Plasmodium. Although the disease-causing forms of the parasite exist only in the human blood, mosquitoes of the genus Anopheles are the obligate vector for transmission. Here, we review the parasite life cycle in the vector and highlight the human and mosquito contributions that limit malaria parasite development in the mosquito host. We address parasite killing in its mosquito host and bottlenecks in parasite numbers that might guide intervention strategies to prevent transmission.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Plasmodium
/
Insect Vectors
/
Life Cycle Stages
/
Anopheles
Limits:
Animals
/
Humans
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2014
Type:
Article
/
Project document
Affiliation country:
United States
Institution/Affiliation country:
Johns Hopkins Bloomberg School of Public Health and Immunology/US
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