Plasmodium vivax malaria elimination: should innovative ideas from the past be revisited?
Mem. Inst. Oswaldo Cruz
;
109(5): 522-524, 19/08/2014.
Article
in English
| LILACS
| ID: lil-720430
ABSTRACT
In the 1950s, the strategy of adding chloroquine to food salt as a prophylaxis against malaria was considered to be a successful tool. However, with the development of Plasmodium resistance in the Brazilian Amazon, this control strategy was abandoned. More than 50 years later, asexual stage resistance can be avoided by screening for antimalarial drugs that have a selective action against gametocytes, thus old prophylactic measures can be revisited. The efficacy of the old methods should be tested as complementary tools for the elimination of malaria.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Plasmodium vivax
/
Primaquine
/
Chloroquine
/
Malaria, Vivax
/
Antimalarials
Limits:
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2014
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Fundação de Medicina Tropical Dr Heitor Vieira Dourado/BR
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