Acroangiodermatitis (pseudo-Kaposi's sarcoma) in an HIV sero-positive patient with syphilis and hepatitis C virus coinfection: clinical and dermatopathological features
An. bras. dermatol
;
89(5): 792-795, Sep-Oct/2014. graf
Article
in English
| LILACS
| ID: lil-720784
ABSTRACT
Acroangiodermatitis is an angioproliferative disease usually related to chronic venous insufficiency, and it is considered a clinical and histological simulator of Kaposi's sarcoma (KS). Immunohistochemistry is the suitable method to differentiate between these two entities. It reveals the following immunostaining profile immunopositivity with anti-CD34 antibody is restricted to the vascular endothelium in acroangiodermatitis, and diffuse in the KS (endothelial cells and perivascular spindle cells); immunopositivity with anti-HHV-8 only in KS cases. We report the case of an HIV seropositive patient without apparent vascular disease, who presented violaceous and brownish erythematous lesions on the feet, and whose histopathology and immunohistochemistry indicated the diagnosis of acroangiodermatitis.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Sarcoma, Kaposi
/
Acrodermatitis
/
Syphilis
/
HIV Seropositivity
/
Hepatitis C
Type of study:
Diagnostic study
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2014
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Santa Casa da Misericórdia do Rio de Janeiro/BR
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