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Efficacy of a lutein-based dye (PhacodyneTM) for visualizing anterior capsulorhexis during cataract surgery by phacoemulsification / Eficácia de corante à base de luteína (PhacodyneTM) para observação da capsulorrexis anterior em cirurgia de facoemulsificação
Vianna, Lucas Monferrari Monteiro; Cohen, Marcos J.; Muccioli, Cristina; Lima, Acácio; Sousa-Martins, Diogo; Maia, Maurício; Belfort Jr, Rubens.
  • Vianna, Lucas Monferrari Monteiro; Universidade Federal de São Paulo. Departamento de Oftalmologia. São Paulo. BR
  • Cohen, Marcos J.; Universidade Federal de São Paulo. Departamento de Oftalmologia. São Paulo. BR
  • Muccioli, Cristina; Universidade Federal de São Paulo. Departamento de Oftalmologia. São Paulo. BR
  • Lima, Acácio; Universidade Federal de São Paulo. Departamento de Oftalmologia. São Paulo. BR
  • Sousa-Martins, Diogo; Universidade Federal de São Paulo. Departamento de Oftalmologia. São Paulo. BR
  • Maia, Maurício; Universidade Federal de São Paulo. Departamento de Oftalmologia. São Paulo. BR
  • Belfort Jr, Rubens; Universidade Federal de São Paulo. Departamento de Oftalmologia. São Paulo. BR
Arq. bras. oftalmol ; 77(3): 173-177, May-Jun/2014. tab, graf
Article in English | LILACS | ID: lil-723834
RESUMO

Purpose:

To evaluate the efficacy and safety of a novel lutein-based dye for the anterior capsulorhexis during phacoemulsification in cataract surgery in humans.

Methods:

Twenty-five eyes from 25 patients were operated by 25 different surgeons who performed continuous circular capsulorhexis (CCC) guided by a lutein-based dye (PhacodyneTM) during cataract surgery by phacoemulsification. A questionnaire assessed the surgeon's opinion regarding the efficacy of the dye. Follow-up examinations were performed at 1, 7, and 30 days post-surgery. Eyes were evaluated by full ophthalmic examination, corneal topography/pachymetry, and corneal endothelial cell count.

Results:

As revealed by the answers to the questionnaire, the dye facilitated the CCC procedure in all eyes. Baseline nuclear cataract classification (according to the Lens Opacities Classification System III; LOCS III) was 3.24 (± 1.12). Preoperative BCVA (logMAR) was 0.89 ± 0.59 and improved to 0.23 ± 0.22 on day 30 after surgery. The intraocular pressure (IOP) remained stable and the inflammatory reaction subsided in all cases within the first 7 days after surgery. The pre-operative values of corneal pachymetry and IOP were similar to those found on follow-up day 30. Loss in endothelial cell number was similar to earlier reports.

Conclusion:

PhacodyneTM was efficient when used for anterior capsulorhexis during cataract surgery by phacoemulsification and showed no signs of toxicity or side effects during the 30-day follow-up period. .
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Trypan Blue / Lutein / Phacoemulsification / Capsulorhexis / Coloring Agents / Anterior Capsule of the Lens Type of study: Evaluation studies / Observational study / Qualitative research Limits: Female / Humans / Male Language: English Journal: Arq. bras. oftalmol Journal subject: Ophthalmology Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal de São Paulo/BR

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Full text: Available Index: LILACS (Americas) Main subject: Trypan Blue / Lutein / Phacoemulsification / Capsulorhexis / Coloring Agents / Anterior Capsule of the Lens Type of study: Evaluation studies / Observational study / Qualitative research Limits: Female / Humans / Male Language: English Journal: Arq. bras. oftalmol Journal subject: Ophthalmology Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal de São Paulo/BR