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Septic arthritis: immunopathogenesis, experimental models and therapy
Colavite, Priscila Maria; Sartori, Alexandrina.
  • Colavite, Priscila Maria; Universidade Estadual Paulista. Instituto de Biociências. Departamento de Microbiologia e Imunologia. Botucatu. BR
  • Sartori, Alexandrina; s.af
Article in English | LILACS | ID: lil-724667
ABSTRACT
Septic arthritis is an inflammatory disease of the joints that is started by an infection whose most common agent is Staphylococcus aureus. In this review we discuss some of the most arthritogenic bacterial factors and the contribution of innate and specific immune mechanisms to joint destruction. Special emphasis is given to the induction of experimental arthritis by S. aureus in mice. The improvement of therapy by association of antibiotics with down-modulation of immunity is also included.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Arthritis / Rats / Staphylococcus Type of study: Prognostic study Limits: Animals Language: English Journal: J. venom. anim. toxins incl. trop. dis Journal subject: Toxicology Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Estadual Paulista/BR

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Full text: Available Index: LILACS (Americas) Main subject: Arthritis / Rats / Staphylococcus Type of study: Prognostic study Limits: Animals Language: English Journal: J. venom. anim. toxins incl. trop. dis Journal subject: Toxicology Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Estadual Paulista/BR