Septic arthritis: immunopathogenesis, experimental models and therapy
J. venom. anim. toxins incl. trop. dis
;
2004/02/2014.
Article
in English
| LILACS
| ID: lil-724667
ABSTRACT
Septic arthritis is an inflammatory disease of the joints that is started by an infection whose most common agent is Staphylococcus aureus. In this review we discuss some of the most arthritogenic bacterial factors and the contribution of innate and specific immune mechanisms to joint destruction. Special emphasis is given to the induction of experimental arthritis by S. aureus in mice. The improvement of therapy by association of antibiotics with down-modulation of immunity is also included.
Full text:
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Index:
LILACS (Americas)
Main subject:
Arthritis
/
Rats
/
Staphylococcus
Type of study:
Prognostic study
Limits:
Animals
Language:
English
Journal:
J. venom. anim. toxins incl. trop. dis
Journal subject:
Toxicology
Year:
2014
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Estadual Paulista/BR
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