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Association among H. pylori virulence markers dupA, cagA and vacA in Brazilian patients
Pereira, Weendelly Nayara; Ferraz, Mariane Avante; Zabaglia, Luanna Munhoz; labio, Roger William de; Orcini, Wilson Aparecido; Ximenez, João Paulo bianchi; Caleman Neto, Agostinho; Payão, Spencer Luiz Marques; Rasmussen, Lucas Trevizani.
  • Pereira, Weendelly Nayara; Universidade do Sagrado Coração. Bauru. BR
  • Ferraz, Mariane Avante; Universidade do Sagrado Coração. Bauru. BR
  • Zabaglia, Luanna Munhoz; Universidade do Sagrado Coração. Bauru. BR
  • labio, Roger William de; Universidade do Sagrado Coração. Bauru. BR
  • Orcini, Wilson Aparecido; Universidade do Sagrado Coração. Bauru. BR
  • Ximenez, João Paulo bianchi; Universidade do Sagrado Coração. Bauru. BR
  • Caleman Neto, Agostinho; Universidade do Sagrado Coração. Bauru. BR
  • Payão, Spencer Luiz Marques; Universidade do Sagrado Coração. Bauru. BR
  • Rasmussen, Lucas Trevizani; Universidade do Sagrado Coração. Bauru. BR
J. venom. anim. toxins incl. trop. dis ; 2004/02/2014.
Article in English | LILACS | ID: lil-724676
ABSTRACT
Only a few Helicobacter pylori-infected individuals develop severe gastric diseases and virulence factors of H. pylori appear to be involved in such clinical outcomes. Duodenal ulcer promoting gene A (dupA) is a novel virulence factor of Helicobacter pylori that is associated with duodenal ulcer development and reduced risk for gastric carcinoma in some populations. The aims of the present study were to determine the presence of dupA gene and evaluate the association among dupA and other virulence factors including cagA and vacA in Brazilian patients. Gastric biopsies were obtained from 205 dyspeptic patients (100 children and 105 adults). DNA was extracted and analyzed for the presence of H. pylori and its virulence factors using the polymerase chain reaction method.
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Full text: Available Index: LILACS (Americas) Main subject: Peptic Ulcer / Virulence / Helicobacter pylori Type of study: Risk factors Limits: Animals Country/Region as subject: South America / Brazil Language: English Journal: J. venom. anim. toxins incl. trop. dis Journal subject: Toxicology Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade do Sagrado Coração/BR

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Full text: Available Index: LILACS (Americas) Main subject: Peptic Ulcer / Virulence / Helicobacter pylori Type of study: Risk factors Limits: Animals Country/Region as subject: South America / Brazil Language: English Journal: J. venom. anim. toxins incl. trop. dis Journal subject: Toxicology Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade do Sagrado Coração/BR