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Presynaptic neuromuscular action of a methanolic extract from the venom of Rhinella schneideri toad
Rostelato-Ferreira, Sandro; Belo, Cháriston A. Dal; Leite, Gildo B; Hyslop, Stephen; Rodrigues-Simioni, Léa.
  • Rostelato-Ferreira, Sandro; Universidade Estadual de Campinas. Faculdade de Ciências Médicas. Departamento de Farmacologia. Campinas. BR
  • Belo, Cháriston A. Dal; Universidade Estadual de Campinas. Faculdade de Ciências Médicas. Departamento de Farmacologia. Campinas. BR
  • Leite, Gildo B; Universidade Estadual de Campinas. Faculdade de Ciências Médicas. Departamento de Farmacologia. Campinas. BR
  • Hyslop, Stephen; Universidade Estadual de Campinas. Faculdade de Ciências Médicas. Departamento de Farmacologia. Campinas. BR
  • Rodrigues-Simioni, Léa; Universidade Estadual de Campinas. Faculdade de Ciências Médicas. Departamento de Farmacologia. Campinas. BR
Article in English | LILACS | ID: lil-724689
Responsible library: BR68.1
ABSTRACT
Rhinella schneideri, previously known as Bufo paracnemis, is a common toad in many regions of Brazil. Its venom exerts important cardiovascular effects on humans and other animals. Although this toad venom has been the subject of intense investigations, little is known about its neuromuscular activity. The neurotoxicity of a methanolic extract of R. schneideri venom was tested on mouse phrenic nerve-diaphragm (PND) preparations mounted for conventional twitch tension recording – in response to indirect stimulation – and for electrophysiological measurements.
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Full text: Available Index: LILACS (Americas) Main subject: Poisons / Neuromuscular Agents / Neurotoxins Limits: Animals Language: English Journal: J. venom. anim. toxins incl. trop. dis Journal subject: Toxicology Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Estadual de Campinas/BR

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Full text: Available Index: LILACS (Americas) Main subject: Poisons / Neuromuscular Agents / Neurotoxins Limits: Animals Language: English Journal: J. venom. anim. toxins incl. trop. dis Journal subject: Toxicology Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Estadual de Campinas/BR