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Hand-foot-and-muuth disease epidemiological staus and relationship with meteorrological variables in guangzhou, southern China, 2008-2012 / Situação epidemiológica e a relação com variáveis meteorológicas da HFMD em Guangzhou, sul da China, 2008-2012
Li, Tiegang; Yang, Zhicong; Liu, Xiangyi; Kang, Yan; Wang, Ming.
  • Li, Tiegang; Guangzhou Center for Disease Control and Prevention. Guangzhou. CN
  • Yang, Zhicong; Guangzhou Center for Disease Control and Prevention. Guangzhou. CN
  • Liu, Xiangyi; Guangzhou Center for Disease Control and Prevention. Guangzhou. CN
  • Kang, Yan; Guangzhou Center for Disease Control and Prevention. Guangzhou. CN
  • Wang, Ming; Guangzhou Center for Disease Control and Prevention. Guangzhou. CN
Rev. Inst. Med. Trop. Säo Paulo ; 56(6): 533-539, Nov-Dec/2014. tab, graf
Article in English | LILACS | ID: lil-725800
ABSTRACT
Hand-foot-and-mouth disease (HFMD) is becoming one of the extremely common airborne and contact transmission diseases in Guangzhou, southern China, leading public health authorities to be concerned about its increased incidence. In this study, it was used an ecological study plus the negative binomial regression to identify the epidemic status of HFMD and its relationship with meteorological variables. During 2008-2012, a total of 173,524 HFMD confirmed cases were reported, 12 cases of death, yielding a fatality rate of 0.69 per 10,000. The annual incidence rates from 2008 to 2012 were 60.56, 132.44, 311.40, 402.76, and 468.59 (per 100,000), respectively, showing a rapid increasing trend. Each 1 °C rise in temperature corresponded to an increase of 9.47% (95% CI 9.36% to 9.58%) in the weekly number of HFMD cases, while a one hPa rise in atmospheric pressure corresponded to a decrease in the number of cases by 7.53% (95% CI -7.60% to -7.45%). Similarly, each one percent rise in relative humidity corresponded to an increase of 1.48% or 3.3%, and a one meter per hour rise in wind speed corresponded to an increase of 2.18% or 4.57%, in the weekly number of HFMD cases, depending on the variables considered in the model. These findings revealed that epidemic status of HFMD in Guangzhou is characterized by high morbidity but low fatality. Weather factors had a significant influence on the incidence of HFMD.
RESUMO
A doença de mão--e-boca (HFMD) está se tornando doença extremamente comum transmitida pelo ar e contato em Guangzhou, sul da China, levando preocupação às autoridades de saúde pública acerca da sua incidência aumentada. Neste estudo foi usada parte ecológica e regressão binomial negativa para identificar o status epidêmico da HFMD e sua relação com variáveis meteorológicas. Durante 2008-2012 um total de 173.524 casos confirmados de HFMD foram apresentados, 12 com morte, elevando o índice de fatalidade a 0,69 por 10.000. As incidências anuais de 2008 a 2010 foram 60,56, 132,44, 311,40, 402,76 e 468,59 por 100.000, respectivamente, mostrando tendência de rápido aumento. Cada 1 °C de aumento da temperatura correspondeu a aumento de 9,47% (95% CI 9,36% a 9,58%) no número semanal de casos de HFMD, enquanto a 1 hPa de aumento da pressão atmosférica correspondeu a decréscimo no número de casos de 7,53% (95% CI - 7,60% a - 7,45%). De maneira semelhante cada aumento de 1% na humidade relativa correspondeu a aumento de 1,48% ou 3,3% e a um aumento de 1 metro por hora na velocidade do vento correspondeu a um aumento de 2,18% ou 4,57%, no número de casos semanais de HFMD, dependendo das variáveis consideradas no modelo. Estes achados revelaram que o status epidêmico do HFMD em Guangzhou é caracterizado por alta morbidade, mas baixa fatalidade. Fatores referentes ao tempo tiveram influência significante na incidência do HFMD.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Atmospheric Pressure / Weather / Hand, Foot and Mouth Disease Type of study: Etiology study / Incidence study / Prognostic study Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Infant, Newborn Country/Region as subject: Asia Language: English Journal: Rev. Inst. Med. Trop. Säo Paulo Journal subject: Tropical Medicine Year: 2014 Type: Article Affiliation country: China Institution/Affiliation country: Guangzhou Center for Disease Control and Prevention/CN

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Full text: Available Index: LILACS (Americas) Main subject: Atmospheric Pressure / Weather / Hand, Foot and Mouth Disease Type of study: Etiology study / Incidence study / Prognostic study Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Infant, Newborn Country/Region as subject: Asia Language: English Journal: Rev. Inst. Med. Trop. Säo Paulo Journal subject: Tropical Medicine Year: 2014 Type: Article Affiliation country: China Institution/Affiliation country: Guangzhou Center for Disease Control and Prevention/CN