Two cases of renal cell cancer during immunobiologic therapy for psoriasis
An. bras. dermatol
;
89(6): 1017-1018, Nov-Dec/2014.
Article
in English
| LILACS
| ID: lil-727640
ABSTRACT
Immunobiologic therapy is indicated for severe forms of psoriasis, resistant to conventional therapy. There is growing concern about their safety profile and possible association with cancer development. This article documents two cases of renal cell cancer during treatment with biologic therapy, reviewing what is described in the literature . The risk of solid tumors as a complication of using TNF-alpha inhibitors is controversial. No conclusion can be drawn from the data in the literature, however, we believe that special attention should be given to those with known risk factors for a specific neoplasm.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Psoriasis
/
Carcinoma, Renal Cell
/
Tumor Necrosis Factor-alpha
/
Immunologic Factors
/
Kidney Neoplasms
Type of study:
Etiology study
/
Risk factors
Limits:
Adult
/
Aged
/
Humans
/
Male
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2014
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Santa Casa da Misericórdia do Rio de Janeiro/BR
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