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Inner and outer segment junction (IS/OS line) integrity in ocular Behçet's disease / Integridade da junção do segmento ınterno e externo (linha IS/OS) na doença de Behçet ocular
Yüksel, Harun; Türkcü, Fatih M.; Şahin, Muhammed; Çinar, Yasin; Cingü, Abdullah K.; Özkurt, Zeynep; Şahin, Alparslan; Ari, Şeyhmus; Çaça, İhsan.
  • Yüksel, Harun; Dicle University Faculty of Medicine. Department of Ophthalmology. Diyarbakir. TR
  • Türkcü, Fatih M.; Dicle University Faculty of Medicine. Department of Ophthalmology. Diyarbakir. TR
  • Şahin, Muhammed; Dicle University Faculty of Medicine. Department of Ophthalmology. Diyarbakir. TR
  • Çinar, Yasin; Dicle University Faculty of Medicine. Department of Ophthalmology. Diyarbakir. TR
  • Cingü, Abdullah K.; Dicle University Faculty of Medicine. Department of Ophthalmology. Diyarbakir. TR
  • Özkurt, Zeynep; Dicle University Faculty of Medicine. Department of Ophthalmology. Diyarbakir. TR
  • Şahin, Alparslan; Dicle University Faculty of Medicine. Department of Ophthalmology. Diyarbakir. TR
  • Ari, Şeyhmus; Dicle University Faculty of Medicine. Department of Ophthalmology. Diyarbakir. TR
  • Çaça, İhsan; Dicle University Faculty of Medicine. Department of Ophthalmology. Diyarbakir. TR
Arq. bras. oftalmol ; 77(4): 219-221, Jul-Aug/2014. tab
Article in English | LILACS | ID: lil-728654
ABSTRACT

Purpose:

In this study, we examined the spectral domain optical coherence tomography (OCT) findings of ocular Behçet's disease (OB) in patients with inactive uveitis. Specifically, we analyzed the inner and outer segment junction (IS/OS line) integrity and the effect of disturbed IS/OS line integrity on visual acuity.

Methods:

Patient files and OCT images of OB patients who had been followed-up between January and June of the year 2013 at the Dicle University Eye Clinic were evaluated retrospectively. Sixty-six eyes of 39 patients were included the study.

Results:

OCT examination of the patients with inactive OB revealed that approximately 25% of the patients had disturbed IS/OS and external limiting membrane (EML) line integrity, lower visual acuity (VA), and lower macular thickness than others. Linear regression analysis revealed that macular thickness was not an independent variable for VA. In contrast, the IS/OS line integrity was an independent variable for VA in inactive OB patients.

Conclusion:

In this study, we showed that the IS/OS line integrity was an independent variable for VA in inactive OB patients. Further prospective studies are needed to evaluate the integrity of the IS/OS line in OB patients. .
RESUMO

Objetivo:

Neste estudo, examinamos os achados da tomografia de coerência óptica (OCT) de domínio espectral na doença de Behçet ocular (OB) em pacientes com uveíte inativa. Especificamente, analisamos a integridade da junção dos segmentos interno e externo (linha IS/OS) e o efeito da alteração da integridade da linha IS/OS na acuidade visual.

Métodos:

Avaliamos retrospectivamente os prontuários e as imagens de OCT dos pacientes com OB examinados entre janeiro e junho de 2013 na Dicle University Eye Clinic. Sessenta e seis olhos de 39 pacientes foram incluídos no estudo.

Resultados:

Análise das imagens de OCT dos pacientes com OB inativa revelou que aproximadamente 25% dos pacientes tinham alterações da integridade da linha IS/OS e da membrana limitante externa (ELM), e apresentavam acuidade visual (VA) e espessura macular menor do que os outros. A análise de regressão linear revelou que a espessura macular não é uma variável independente para VA. Por outro lado, a integridade da linha IS/OS foi uma variável independente para VA em pacientes com OB inativa.

Conclusão:

Neste estudo, nós mostramos que a integridade da linha IS/OS foi uma variável independente para a VA em pacientes com OB inativa. Precisamos de mais estudos prospectivos para avaliar a integridade da linha IS/OS em pacientes com OB. .
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Visual Acuity / Behcet Syndrome / Tomography, Optical Coherence / Retinal Photoreceptor Cell Inner Segment / Retinal Photoreceptor Cell Outer Segment Type of study: Observational study Limits: Humans Language: English Journal: Arq. bras. oftalmol Journal subject: Ophthalmology Year: 2014 Type: Article Affiliation country: Turkey Institution/Affiliation country: Dicle University Faculty of Medicine/TR

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Full text: Available Index: LILACS (Americas) Main subject: Visual Acuity / Behcet Syndrome / Tomography, Optical Coherence / Retinal Photoreceptor Cell Inner Segment / Retinal Photoreceptor Cell Outer Segment Type of study: Observational study Limits: Humans Language: English Journal: Arq. bras. oftalmol Journal subject: Ophthalmology Year: 2014 Type: Article Affiliation country: Turkey Institution/Affiliation country: Dicle University Faculty of Medicine/TR