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Evolution in the profile of thyroid cancer cases treated in an oncology reference service: what changed in the last 20 years / Evolução no perfil dos casos de câncer de tireoide tratados em um serviço de referência em oncologia: o que mudou nos últimos 20 anos
Lira, Renan Bezerra; Carvalho, Genival Barbosa de; Gonçalves Filho, João; Kowalski, Luiz Paulo.
  • Lira, Renan Bezerra; Department of Head and Neck Surgery and Otorhinolaryngology. São Paulo. BR
  • Carvalho, Genival Barbosa de; Department of Head and Neck Surgery and Otorhinolaryngology. São Paulo. BR
  • Gonçalves Filho, João; Department of Head and Neck Surgery and Otorhinolaryngology. São Paulo. BR
  • Kowalski, Luiz Paulo; Department of Head and Neck Surgery and Otorhinolaryngology. São Paulo. BR
Rev. Col. Bras. Cir ; 41(5): 320-324, Sep-Oct/2014. graf
Article in English | LILACS | ID: lil-729965
ABSTRACT

Objective:

To evaluate the characteristics of thyroid carcinoma cases treated at a reference hospital for cancer between 2008 and 2010.

Methods:

we studied 807 cases and analyzed the following clinicopathologic variables symptoms, risk factors, diagnostic tests, staging, histological type, treatment performed and complications.

Results:

Females were more affected, with 660 cases (82%). The average age at diagnosis was 44.5 years. Prior exposure to ionizing radiation was reported by 22 (3%) patients, a family history of thyroid cancer by 89 (11%), and 289 (36%) individuals reported other types of cancer in the family. The fine needle aspiration biopsy was the main parameter for surgical indication and was suggestive of carcinoma in 463 patients (57%). Papillary carcinoma was the most common histological type, with 780 cases (96.6%). There were 728 (90%) total thyroidectomies, 43 (5.3%) reoperations or partial thyroidectomies followed by totalization, 23 (2.8%) extended thyroidectomies and only 13 (1.6%) partial thyroidectomies (lobectomy with isthmectomy). Neck dissection associated with thyroidectomy was done in 158 patients (19.5%). We observed a predominance of tumors classified as T1 in 602 (74.6%) patients. Transient hypocalcemia was the most frequent complication.

Conclusion:

The results show that the worldwide increase in the incidence of thyroid cancer has changed the profile of patients seen at a referral service. In addition, there were changes in the type of surgical treatment used, with increased use of total thyroidectomy in relation to partial and subtotal ones, and decreased use of elective neck dissections. .
RESUMO

Objetivo:

avaliar características casos de carcinoma de tireoide atendidos em um hospital de referência em câncer entre 2008 e 2010.

Métodos:

foram analisadas variáveis clínico-patológicas de 807 casos tratados em três anos sintomas, fatores de risco, exames de diagnóstico, estadiamento, tipo histológico, tratamento realizado e complicações.

Resultados:

o sexo feminino foi o mais acometido com 660 casos (82%). A média de idade ao diagnóstico foi 44,5 anos. A exposição prévia à radiação ionizante foi referida por 22 (3%) pacientes, a história familiar de câncer de tireoide por 89 (11%) pacientes e 289 (36%) pacientes relataram outros tipos de câncer na família. A punção aspirativa por agulha fina foi o principal parâmetro para indicação operatória e foi sugestiva de carcinoma em 463 pacientes (57%). O carcinoma papilífero foi o tipo histológico mais incidente, com 780 casos (96,6%). Foram realizadas 728 (90%) tireoidectomias totais, 43 (5,3%) reoperações ou tireoidectomias parciais seguidas de totalização, 23 (2,8%) tireoidectomias ampliadas e apenas 13 (1,6%) tireoidectomias parciais (lobectomia com istmectomia). O esvaziamento cervical, associado à tireoidectomia, foi feito em 158 pacientes (19,5%). Observamos predomínio dos tumores classificados como T1 em 602 (74,6%) dos pacientes. A hipocalcemia transitória foi a complicação mais frequente.

Conclusão:

os resultados mostram que o aumento mundial da incidência do câncer de tireoide alterou o perfil dos pacientes atendidos em serviço de referência. Além disso, ocorreram mudanças no tipo de tratamento cirúrgico empregado, com aumento no uso da tireoidectomia total em relação às parciais e subtotais e diminuição ...
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Thyroidectomy / Thyroid Neoplasms Type of study: Diagnostic study / Etiology study / Incidence study / Observational study / Risk factors Limits: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male Language: English Journal: Rev. Col. Bras. Cir Journal subject: General Surgery Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: Department of Head and Neck Surgery and Otorhinolaryngology/BR

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Full text: Available Index: LILACS (Americas) Main subject: Thyroidectomy / Thyroid Neoplasms Type of study: Diagnostic study / Etiology study / Incidence study / Observational study / Risk factors Limits: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male Language: English Journal: Rev. Col. Bras. Cir Journal subject: General Surgery Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: Department of Head and Neck Surgery and Otorhinolaryngology/BR