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Pulmonary adenocarcinoma in cattle / Adenocarcinoma pulmonar en bovinos
Sousa Z, Diogo; Rivera C, Luis; Quevedo C, Didier; Gorino, Ana Claudia; Biagio C, Simone; Laufer A, Renée.
  • Sousa Z, Diogo; São Paulo State University. Faculty of Veterinary and Zootechnical Medicine. Clinical Veterinary Department. São Paulo. BR
  • Rivera C, Luis; São Paulo State University. Faculty of Veterinary and Zootechnical Medicine. Clinical Veterinary Department. São Paulo. BR
  • Quevedo C, Didier; São Paulo State University. Faculty of Veterinary and Zootechnical Medicine. Clinical Veterinary Department. São Paulo. BR
  • Gorino, Ana Claudia; São Paulo State University. Faculty of Veterinary and Zootechnical Medicine. Clinical Veterinary Department. São Paulo. BR
  • Biagio C, Simone; São Paulo State University. Faculty of Veterinary and Zootechnical Medicine. Clinical Veterinary Department. São Paulo. BR
  • Laufer A, Renée; São Paulo State University. Faculty of Veterinary and Zootechnical Medicine. Clinical Veterinary Department. São Paulo. BR
Rev. MVZ Córdoba ; 19(3): 4358-4363, Sept.-Dec. 2014. ilus, tab
Article in English | LILACS, COLNAL | ID: lil-730970
ABSTRACT
The Macroscopic, histological and immunohistochemical aspects of lung acinar adenocarcinoma and the presence of nodules in the abdominal cavity of an adult female bovine are reported. In the necropsy analysis samples were collected from the: lung, heart, spleen, liver, pancreas, kidney, uterus, intestine, brain, and from nodules found in the lung and abdominal cavity, which were routinely processed to be stained by hematoxylin-eosin and for an immunohistochemistry exam with the antibodies: cytokeratin (dilution 1:200 µL) and vimentin (dilution 1:1000 µL). The histopathological examination revealed neoplastic epithelial cells with acini formation. The immunohistochemical examination of the tumor cells showed positive marking for cytokeratin and the absence of marking for vimentin. According to anatomical, morphological, and histopathological findings, as well as the result of the immunohistochemical examination, the tumor was characterized as lung acinar adenocarcinoma.
RESUMEN
Se relatan los aspectos macroscópicos, histológicos e inmunohistoquímicos de un adenocarcinoma acinar pulmonar y la presencia de nódulos en la cavidad abdominal en una hembra bovina adulta. En el análisis necroscópico fueron colectados fragmentos de: pulmón, corazón, bazo, hígado, páncreas, riñón, útero, intestino, encéfalo y de los nódulos hallados en pulmón y cavidad abdominal, los cuales fueron procesados rutinariamente para ser teñidos mediante Hematoxilina-Eosina y para examen inmunohistoquímico con los anticuerpos: citoqueratina (con dilución 1:200 µL) y vimentina (dilución 1:1000 µL). El examen histopatológico reveló células epiteliales neoplásicas con formación de acinos. El examen inmunohistoquímico de las células neoplásicas demostró marcación positiva para citoqueratina y ausencia de marcación para vimentina. De acuerdo con los hallazgos anatómicos, morfológicos, histopatológico, y el resultado del examen inmunohistoquímico, se logró caracterizar el tumor como adenocarcinoma acinar pulmonar.
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Full text: Available Index: LILACS (Americas) Main subject: Immunochemistry Language: English Journal: Rev. MVZ Córdoba Journal subject: Veterinary Medicine Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: São Paulo State University/BR

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Full text: Available Index: LILACS (Americas) Main subject: Immunochemistry Language: English Journal: Rev. MVZ Córdoba Journal subject: Veterinary Medicine Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: São Paulo State University/BR