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Effects of a continuous rate infusion of butorphanol in isoflurane-anesthetized horses on cardiorespiratory parameters, recovery quality, gastrointestinal motility and serum cortisol concentrations
Dias, Bianca Paludeto; Araújo, Marcelo Augusto de; Deschk, Maurício; Trein, Thomas Alexander; Pinheiro, Nirmem Carlos; Perri, Silvia Helena Venturolli; Rodrigues, Celso Antônio; Santos, Paulo Sergio Patto dos.
  • Dias, Bianca Paludeto; Sao Paulo State University. Faculty of Veterinary Medicine. Araçatuba. BR
  • Araújo, Marcelo Augusto de; Sao Paulo State University. Faculty of Veterinary Medicine. Araçatuba. BR
  • Deschk, Maurício; Sao Paulo State University. Faculty of Veterinary Medicine. Araçatuba. BR
  • Trein, Thomas Alexander; Sao Paulo State University. Faculty of Veterinary Medicine. Araçatuba. BR
  • Pinheiro, Nirmem Carlos; Sao Paulo State University. Faculty of Veterinary Medicine. Araçatuba. BR
  • Perri, Silvia Helena Venturolli; Sao Paulo State University. Faculty of Veterinary Medicine. Araçatuba. BR
  • Rodrigues, Celso Antônio; Sao Paulo State University. Faculty of Veterinary Medicine. Araçatuba. BR
  • Santos, Paulo Sergio Patto dos; Sao Paulo State University. Faculty of Veterinary Medicine. Araçatuba. BR
Acta cir. bras ; 29(12): 801-806, 12/2014. tab, graf
Article in English | LILACS | ID: lil-731025
ABSTRACT

PURPOSE:

To assess the cardiorespiratory parametes, recovery, gastrointestinal motility and serum cortisol concentrations in horses anesthetized with isoflurane with or without a continuous rate infusion (CRI) of butorphanol for orchiectomy.

METHODS:

Twelve adult, intact, male horses weighing 332 ± 55 kg were included in the study. Xilazine was administered as premedication. Anesthesia was induced with ketamine and midazolam and maintained with isoflurane. Butorphanol (0.025 mg kg-1 bolus) or an equivalent volume of saline (0.9%) was given intravenously followed by a CRI of butorphanol (BG) (13 µg kg-1 hour-1) or saline (CG). Cardiorespiratory variables were recorded before (T0) and every 15 minutes for 75 minutes after the start of infusion. Serum cortisol concentration was measured at T0 and 60 minutes, and 30 minutes and 19 hours after the horse stood up. Recovery from anesthesia was evaluated using a scoring system. Gastrointestinal motility was evaluated before anesthesia and during 24 hours after recovery.

RESULTS:

There were no significant differences between groups in cardiopulmonary variables, or recovery scores or serum cortisol concentrations. A reduction in gastrointestinal motility was recorded for 60 minutes in BG.

CONCLUSIONS:

Continuous rate infusion of butorphanol in horses anesthetized with isoflurane did not adversely affect the cardiopulmonary variables monitored, or recovery scores. A small but statistically significant reduction in gastrointestinal motility occurred in the butorphanol group. .
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Infusion Pumps / Anesthesia Recovery Period / Butorphanol / Respiratory Rate / Gastrointestinal Motility / Analgesics, Opioid Type of study: Prognostic study Limits: Animals Language: English Journal: Acta cir. bras Journal subject: General Surgery / Procedimentos Cir£rgicos Operat¢rios Year: 2014 Type: Article / Project document Affiliation country: Brazil Institution/Affiliation country: Sao Paulo State University/BR

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Full text: Available Index: LILACS (Americas) Main subject: Infusion Pumps / Anesthesia Recovery Period / Butorphanol / Respiratory Rate / Gastrointestinal Motility / Analgesics, Opioid Type of study: Prognostic study Limits: Animals Language: English Journal: Acta cir. bras Journal subject: General Surgery / Procedimentos Cir£rgicos Operat¢rios Year: 2014 Type: Article / Project document Affiliation country: Brazil Institution/Affiliation country: Sao Paulo State University/BR