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Características clínicas y anatomo-patológicas de las pacientes que ingresaron al Programa de Control de Tuberculosis con diagnóstico de tuberculosis de mama / Clinical and pathological features of patients treated at the tuberculosis control program with the diagnosis of breast tuberculosis
Tafur, Karla; Cáceres, Jaime; Accinelli, Roberto.
  • Tafur, Karla; Hospital Nacional Cayetano Heredia. Lima. PE
  • Cáceres, Jaime; Hospital Nacional Cayetano Heredia. Lima. PE
  • Accinelli, Roberto; Hospital Nacional Cayetano Heredia. Lima. PE
Rev. méd. hered ; 25(4): 215-222, oct. 2014. tab
Article in Spanish | LILACS, LIPECS | ID: lil-735483
RESUMEN

Objetivo:

Describir las características clínicas y anatomo-patológicas de pacientes que ingresaron con diagnóstico de TB de mama al Programa de control de Tuberculosis (PCT) de un hospital general. Material y

métodos:

Se incluyeron los casos registrados en el PCT como TB de mama en cuyo informe anatomo-patológico figuraba inflamación crónica granulomatosa. Se revisaron las historias clínicas y revaluaron las biopsias de mama.

Resultados:

Se incluyeron 69 mujeres con edad promedio 35,79 ± 7,94 años. Las manifestaciones más frecuentes fueron presencia de nódulo (89,86%), dolor (89,86%) y signos inflamatorios (40,58%). La revaluación de la biopsia mostró granulomas de tipo supurado, con células gigantes multinucleadas tipo Langhans y cuerpo extraño, sin necrosis caseosa, localizados a nivel de la unidad ducto lobular (UDL) y extra-UDL en 85,51 % de los casos. Solo en 3 casos se observó bacilos ácido alcohol resistente en la secreción o tejido de mama. Todos los casos recibieron tratamiento antituberculoso. Treinta y ocho casos tuvieron seguimiento, de ellos 73,68% presentó persistencia o recurrencia al menos un mes después del inicio de tratamiento antituberculoso.

Conclusiones:

Todos los casos del estudio fueron mujeres, la mayoría presentaron nódulo, dolor o signos de inflamación en mama, sin síntomas o signos sistémicos y con presencia de granulomas supurados, sin necrosis caseosa. A pesar de recibir tratamiento antituberculoso en todos los casos, cerca del 75% con seguimiento de al menos un mes presentaron persistencia o recurrencia clínica. (AU)
ABSTRACT

Objective:

To describe clinical and pathological features of patients treated at the tuberculosis (TB) control program (TCP) with the diagnosis of breast TB in a general hospital.

Methods:

Patients registered at the TCP with the pathological diagnosis of chronic granulomatous mastitis were included. Clinical and pathological slides were reviewed.

Results:

A total of 69 women were included; mean age was 35.79 ± 7.94 years of age. The most common clinical manifestations were a nodular lesion (89.96%), pain (89.96%) and inflammatory signs (4058%). Reevaluation of biopsies showed suppurated granulomas with Langhans´ multinucleated giant cells without caseuous necrosis located at the duct-lobular (DL) and extra DL areas in 85.1% of cases. Acid-fast bacilli were seen in only 3 cases. All cases received anti TB treatment. Thirty-eight patients had follow-up, 73.68% of them had recurrence or persistence at least one month after starting anti TB treatment.

Conclusions:

Nodular lesions with pain and inflammatory signs in absence of systemic symptoms, and suppurated granulomas without caseuous necrosis were the most frequent findings. Despite receiving anti TB treatment, almost 75% of patients with follow-up had persistence or clinical recurrence. (AU)
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Tuberculosis / Granulomatous Mastitis Type of study: Diagnostic study Limits: Adult / Female / Humans Language: Spanish Journal: Rev. méd. hered Year: 2014 Type: Article Institution/Affiliation country: Hospital Nacional Cayetano Heredia/PE

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Full text: Available Index: LILACS (Americas) Main subject: Tuberculosis / Granulomatous Mastitis Type of study: Diagnostic study Limits: Adult / Female / Humans Language: Spanish Journal: Rev. méd. hered Year: 2014 Type: Article Institution/Affiliation country: Hospital Nacional Cayetano Heredia/PE