Alopecia secondary to anti-tumor necrosis factor-alpha therapy
An. bras. dermatol
;
90(2): 232-235, Mar-Apr/2015. graf
Article
in English
| LILACS
| ID: lil-741064
ABSTRACT
Biologic drugs represent a substantial progress in the treatment of chronic inflammatory immunologic diseases. However, its crescent use has revealed seldom reported or unknown adverse reactions, mainly associated with anti-tumor necrosis factor (anti-TNF). Psoriasiform cutaneous reactions and few cases of alopecia can occur in some patients while taking these drugs. Two cases of alopecia were reported after anti-TNF therapy. Both also developed psoriasiform lesions on the body. This is the second report about a new entity described as 'anti-TNF therapy-related alopecia', which combines clinical and histopathological features of both alopecia areata and psoriatic alopecia. The recognition of these effects by specialists is essential for the proper management and guidance of these patients.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Psoriasis
/
Crohn Disease
/
Anti-Inflammatory Agents, Non-Steroidal
/
Tumor Necrosis Factor-alpha
/
Alopecia
/
Antibodies, Monoclonal
Type of study:
Practice guideline
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2015
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Faculdade de Medicina do ABC/BR
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