Características epidemiológicas del síndrome de Guillain-Barré en población chilena: estudio hospitalario en un período de 7 años / Clinical features of Guillain-Barré syndrome in 41 patients admitted to a public hospital
Rev. méd. Chile
;
143(2): 183-189, feb. 2015. graf, tab
Article
in Spanish
| LILACS
| ID: lil-742569
ABSTRACT
Background:
Guillain-Barré syndrome (GBS) is the commonest cause of acute flaccid paralysis worldwide, with an incidence of 0.6-4 per 100.000 inhabitants per year. It affects all age groups and carries an incapacity burden of up to 20%.Aim:
To describe the features of GBS in adult Chilean patients admitted to a tertiary care hospital. Material andMethods:
Review of medical records of 41 patients aged 17 to 81 years (30 males) admitted to a public hospital with the diagnosis of GBS between 2003 and 2009. According to clinical and electrophysiological criteria, the patients were classified into different varieties of GBS.Results:
The incidence of GBS was higher in males (2.71) and the demyelinated GBS variety was found in 66% of cases. According to the Hughes disability score, patients treated with plasmapheresis, showed non-statistically significant better outcomes than those treated with intravenous immunoglobulin.Conclusions:
In this group of patients the demyelinated variety of GBS was more common than the axonal type. Although not statistically significant, the better response to plasmapheresis is encouraging and should prompt a controlled study.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Social Class
/
Metabolic Syndrome
/
Renal Insufficiency, Chronic
/
Dyslipidemias
Type of study:
Etiology study
/
Incidence study
/
Observational study
/
Prevalence study
/
Risk factors
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Chile
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2015
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Hospital del Salvador/CL
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