Quality of life after high-dose-rate brachytherapy monotherapy for prostate cancer
Int. braz. j. urol
;
41(1): 40-45, jan-feb/2015. tab, graf
Article
in English
| LILACS
| ID: lil-742862
ABSTRACT
Purpose There is little information in the literature on health-related quality of life (HRQOL) changes due to high-dose-rate (HDR) brachytherapy monotherapy for prostate cancer. Materials and Methods We conducted a prospective study of HRQOL changes due to HDR brachytherapy monotherapy for low risk or favorable intermediate risk prostate cancer. Sixty-four of 84 (76%) patients who were treated between February 2011 and April 2013 completed 50 questions comprising the Expanded Prostate Cancer Index Composite (EPIC) before treatment and 6 and/or 12 months after treatment. Results Six months after treatment, there was a significant decrease (p<0.05) in EPIC urinary, bowel, and sexual scores, including urinary overall, urinary function, urinary bother, urinary irritative, bowel overall, bowel bother, sexual overall, and sexual bother scores. By one year after treatment, EPIC urinary, bowel, and sexual scores had increased and only the bowel overall and bowel bother scores remained significantly below baseline values. Conclusions HDR brachytherapy monotherapy is well-tolerated in patients with low and favorable intermediate risk prostate cancer. EPIC urinary and sexual domain scores returned to close to baseline 12 months after HDR brachytherapy. .
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Prostatic Neoplasms
/
Quality of Life
/
Brachytherapy
Type of study:
Observational study
/
Risk factors
Limits:
Aged
/
Aged80
/
Humans
/
Male
Language:
English
Journal:
Int. braz. j. urol
Journal subject:
Urology
Year:
2015
Type:
Article
Affiliation country:
United States
Institution/Affiliation country:
Moffitt Cancer Center/US
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