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Short-term prophylaxis with ciprofloxacin in extended 16-core prostate biopsy
Chambó, Renato Caretta; Tsuji, Fábio Hissachi; Yamamoto, Hamilton Akihissa; Jesus, Carlos Márcio Nóbrega de.
  • Chambó, Renato Caretta; São Paulo State University. Botucatu Medical School. Botucatu. BR
  • Tsuji, Fábio Hissachi; São Paulo State University. Botucatu Medical School. Botucatu. BR
  • Yamamoto, Hamilton Akihissa; São Paulo State University. Botucatu Medical School. Botucatu. BR
  • Jesus, Carlos Márcio Nóbrega de; São Paulo State University. Botucatu Medical School. Botucatu. BR
Int. braz. j. urol ; 41(1): 46-56, jan-feb/2015. tab, graf
Article in English | LILACS | ID: lil-742884
ABSTRACT
Objective To evaluate the safety, efficacy and possible complications of 16-core transrectal prostate biopsies using two doses of ciprofloxacin for prophylaxis of infectious complications. Materials and Methods Sixteen-core prostate biopsies were performed on a number of patients with different signs of potential prostate cancer. Complications were assessed both during the procedure and one week later. After the procedure, urine samples were collected for culture. The rate of post-biopsy complications, hospital visits and hospitalizations were also analyzed. Ciprofloxacin (500 mg) was administered two hours before, and eight hours after the procedure. Results The overall rate of post-biopsy complications was 87.32%, being 5.4% of those considered major complications due to hemorrhage, or to urinary retention. Eight patients required hospital treatment post-biopsy. Fever occurred in just one patient (0.29%). There was no incidence of orchitis, epididymitis, prostatitis, septicemia, hospitalization, or death. The urine culture showed positive results in five patients (2.15%). Conclusion One-day prophylaxis with ciprofloxacin proved to be safe and effective in the prevention of infectious complications following 16-core prostate biopsies. .
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Postoperative Complications / Prostate / Prostatic Neoplasms / Ciprofloxacin / Antibiotic Prophylaxis / Anti-Bacterial Agents Type of study: Etiology study / Evaluation studies / Observational study Limits: Humans / Male Language: English Journal: Int. braz. j. urol Journal subject: Urology Year: 2015 Type: Article Affiliation country: Brazil Institution/Affiliation country: São Paulo State University/BR

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Full text: Available Index: LILACS (Americas) Main subject: Postoperative Complications / Prostate / Prostatic Neoplasms / Ciprofloxacin / Antibiotic Prophylaxis / Anti-Bacterial Agents Type of study: Etiology study / Evaluation studies / Observational study Limits: Humans / Male Language: English Journal: Int. braz. j. urol Journal subject: Urology Year: 2015 Type: Article Affiliation country: Brazil Institution/Affiliation country: São Paulo State University/BR