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Liver-specific magnetic resonance contrast medium in the evaluation of chronic liver disease / Aplicações do contraste hepato-específico de ressonância magnética nas hepatopatias crônicas
Reis, Marcio Augusto Correia Rodrigues dos; Baroni, Ronaldo Hueb.
  • Reis, Marcio Augusto Correia Rodrigues dos; Hospital Israelita Albert Einstein. São Paulo. BR
  • Baroni, Ronaldo Hueb; Hospital Israelita Albert Einstein. São Paulo. BR
Einstein (Säo Paulo) ; 13(2): 326-329, Apr-Jun/2015. graf
Article in English | LILACS | ID: lil-751413
ABSTRACT
ABSTRACT The hepatobiliary-specific contrast medium (gadoxetic acid – Primovist®) is primarily used to improve detection and characterization of focal hepatic lesions, such as in chronic liver disease patients with suspected hepatocellular carcinoma. Since the contrast medium is selectively taken up by functioning hepatocytes in the late hepatobiliary phase, it helps to detect typical hepatocellular carcinoma, which show low signal intensity on this phase. This imaging feature also assists in differentiating regenerative/dysplastic nodules from early hepatocellular carcinomas (with over 90% accuracy), as well as hypervascular hepatocellular carcinomas from arterial pseudo-enhancement foci. Future perspectives include its use in quantification of hepatic function and fibrosis.
RESUMO
RESUMO O contraste hepato-específico (ácido gadoxético – Primovist®) tem como utilidade principal melhorar a detecção e a caracterização de lesões hepáticas focais, por exemplo, em hepatopatas crônicos com suspeita de hepatocarcinoma. Por apresentar captação seletiva por hepatócitos funcionantes na fase hepatobiliar tardia, auxilia na detecção de hepatocarcinomas típicos – a maioria dos quais apresentando hipossinal nessa fase. Essa característica de imagem também auxilia na diferenciação entre nódulos regenerativos/ displásicos e hepatocarcinomas precoces (com mais de 90% de acurácia), e entre hepatocarcinomas hipervascularizados e focos de pseudorrealce arterial. Perspectivas futuras promissoras incluem sua utilização na quantificação de função e de fibrose hepáticas.
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Full text: Available Index: LILACS (Americas) Main subject: Magnetic Resonance Imaging / Carcinoma, Hepatocellular / Contrast Media / Gadolinium DTPA / Liver Neoplasms Type of study: Diagnostic study Limits: Animals / Humans Language: English Journal: Einstein (Säo Paulo) Journal subject: Medicine Year: 2015 Type: Article Affiliation country: Brazil Institution/Affiliation country: Hospital Israelita Albert Einstein/BR

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Full text: Available Index: LILACS (Americas) Main subject: Magnetic Resonance Imaging / Carcinoma, Hepatocellular / Contrast Media / Gadolinium DTPA / Liver Neoplasms Type of study: Diagnostic study Limits: Animals / Humans Language: English Journal: Einstein (Säo Paulo) Journal subject: Medicine Year: 2015 Type: Article Affiliation country: Brazil Institution/Affiliation country: Hospital Israelita Albert Einstein/BR