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Prospective study of the link between overweight/obesity and diabetes incidence among Mexican older adults: 2001-2012 / Estudio prospectivo de la asociación entre sobrepeso/obesidad e incidencia de diabetes en adultos mayores en México: 2001 -2012
Pinto, Guido; Beltrán-Sánchez, Hiram.
  • Pinto, Guido; University of Wisconsin-Madison. Center for Demography & Ecology. Madison. US
  • Beltrán-Sánchez, Hiram; University of Wisconsin-Madison. Center for Demography & Ecology. Madison. US
Salud pública Méx ; 57(supl.1): s15-s21, 2015. ilus, tab
Article in English | LILACS | ID: lil-751545
ABSTRACT
Objective. To prospectively assess the relationship between overweight/obesity and incidence of type 2 diabetes mellitus (T2DM) among Mexicans aged 50+, assessing effects of age, genetic predisposition, education, physical activity, and place of residence. Materials and methods. The Mexican Health and Aging Study (MHAS) was used to prospectively follow respondents free of diabetes in 2001 who became diabetic by 2012. Multivariate random effects logistic regression was used to assess covariates effects on the incidence of T2DM. Results. Obese or overweight individuals at baseline (2001) were about 3 and 2 times, respectively, significantly more likely to become diabetic by 2012. Genetic predisposition increases the risk of diabetes by about three times compared to those with no family history of diabetes. Conclusion. Overweight/obesity and genetic predisposition are the primary drivers of diabetes incidence among Mexican older adults. Reducing body weight and having access to health care may amel iorate the disease burden of T2DM.
RESUMEN
Objetivo. Cuantificar prospectivamente la relación entre sobrepeso/obesidad e incidencia de diabetes entre mexicanos mayores de 50 años mediante la medición de los efectos de la edad, predisposición genética, educación, actividad física y lugar de residencia. Material y métodos. Se utilizó el Estudio Nacional de Salud y Envejecimiento en México (Enasem) para seguir a adultos mayores sin diabetes en 2001 y que se convirtieron en diabéticos en 2012. Se utilizó el modelo de regresión logística de efectos aleatorios para cuantificar el efecto de covariables en la incidencia de diabetes. Resultados. Quienes tenían obesidad y sobrepeso en 2001 fueron 3 y 2 veces más propensos a adquirir diabetes en 2012, respectivamente. La predisposición genética aumentó tres veces el riesgo de padecer diabetes en comparación con aquéllos sin historia familiar de diabetes. Conclusiones. Sobrepeso, obesidad y predisposición genética son causantes de diabetes en adultos mayores mexicanos. Reducción de peso y acceso a atención de salud podrían reducir las consecuencias que tiene la diabetes.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Diabetes Mellitus, Type 2 / Overweight Type of study: Controlled clinical trial / Etiology study / Incidence study / Observational study / Prognostic study / Risk factors / Screening study Limits: Aged / Female / Humans / Male Country/Region as subject: Mexico Language: English Journal: Salud pública Méx Journal subject: Public Health Year: 2015 Type: Article Affiliation country: United States Institution/Affiliation country: University of Wisconsin-Madison/US

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Full text: Available Index: LILACS (Americas) Main subject: Diabetes Mellitus, Type 2 / Overweight Type of study: Controlled clinical trial / Etiology study / Incidence study / Observational study / Prognostic study / Risk factors / Screening study Limits: Aged / Female / Humans / Male Country/Region as subject: Mexico Language: English Journal: Salud pública Méx Journal subject: Public Health Year: 2015 Type: Article Affiliation country: United States Institution/Affiliation country: University of Wisconsin-Madison/US