Addition of nerve growth factor to the interior of a tubular prosthesis increases sensory neuron regeneration in vivo
Braz. j. med. biol. res
;
22(6): 691-4, June 1989. ilus
Article
in English
| LILACS
| ID: lil-75165
ABSTRACT
The sciatic nerve of adult mice was transected and the proximal and distal nerve stumps were sutured into a polyethylene tube. The tubes were implanted either umpty, or the lumen was filled with pure collagen or a mixture of collagen/nerve trowth factor (NGF). Six weeks later, cells in the L3-L5 dorsal root ganglia (DRG) were retrogradely filled with horseradish perocidase (HRP). The data demonstrate that the addition of NGF to the interior of the tubular prosthesis can significantly increase the regeneration rate of sensory neurons
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Index:
LILACS (Americas)
Main subject:
Sciatic Nerve
/
Nerve Growth Factors
/
Nerve Regeneration
/
Neurons, Afferent
Limits:
Animals
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
1989
Type:
Article
/
Congress and conference
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