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Reacción por drogas con eosinofilia y síntomas sistémicos (síndrome de DRESS): Estudio retrospectivo de nueve casos / Dress syndrome: Report of nine cases
Ocampo-Garza, Jorge; Ocampo-Garza, Sonia Sofía; Martínez-Villarreal, José Darío; Barbosa-Moreno, Laura Elena; Guerrero-González, Guillermo Antonio; Ocampo-Candiani, Jorge.
  • Ocampo-Garza, Jorge; Universidad Autónoma de Nuevo León. Hospital Universitario Dr. José Eleuterio González. Servicio de Dermatología. Monterrey. MX
  • Ocampo-Garza, Sonia Sofía; Universidad Autónoma de Nuevo León. Hospital Universitario Dr. José Eleuterio González. Servicio de Dermatología. Monterrey. MX
  • Martínez-Villarreal, José Darío; Universidad Autónoma de Nuevo León. Hospital Universitario Dr. José Eleuterio González. Servicio de Dermatología. Monterrey. MX
  • Barbosa-Moreno, Laura Elena; Universidad Autónoma de Nuevo León. Hospital Universitario Dr. José Eleuterio González. Servicio de Dermatología. Monterrey. MX
  • Guerrero-González, Guillermo Antonio; Universidad Autónoma de Nuevo León. Hospital Universitario Dr. José Eleuterio González. Servicio de Dermatología. Monterrey. MX
  • Ocampo-Candiani, Jorge; Universidad Autónoma de Nuevo León. Hospital Universitario Dr. José Eleuterio González. Servicio de Dermatología. Monterrey. MX
Rev. méd. Chile ; 143(5): 577-583, ilus, tab
Article in Spanish | LILACS | ID: lil-751702
ABSTRACT

Background:

DRESS Syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) is an uncommon disease caused by drugs. It is characterized by a polymorphic disseminated eruption with fever and multiple organ dysfunction.

Aim:

To report the etiology, characteristics, treatment, prognosis, and follow up of patients with DRESS Syndrome admitted to a clinical hospital. Material and

Methods:

Review of medical records of patients admitted for drug reactions, selecting those patients complying with clinical criteria for DRESS Syndrome. Drugs used during three months prior to the onset of symptoms were evaluated as possible causes of the disease.

Results:

Nine patients aged 16 to 68 years (six males) complied with the clinical criteria for the disease. The causative medications were carbamazepine in three patients, phenytoin in three, antituberculous drugs in two and amoxicillin in one. All were treated with systemic steroids with a complete clinical resolution.

Conclusions:

DRESS syndrome is usually underdiagnosed and has a good response to systemic steroids.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Dexamethasone / Prednisone / Drug Hypersensitivity Syndrome Type of study: Diagnostic study / Etiology study / Observational study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged / Female / Humans / Male Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2015 Type: Article Affiliation country: Mexico Institution/Affiliation country: Universidad Autónoma de Nuevo León/MX

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Full text: Available Index: LILACS (Americas) Main subject: Dexamethasone / Prednisone / Drug Hypersensitivity Syndrome Type of study: Diagnostic study / Etiology study / Observational study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged / Female / Humans / Male Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2015 Type: Article Affiliation country: Mexico Institution/Affiliation country: Universidad Autónoma de Nuevo León/MX