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Expression of human chorionic gonadotropin (ßhCG) in pre-eclamptic placenta / Expresión de gonadotropina coriónica humana (ßhCG) en placenta preeclámptica
Ekinci, C; Tahaoglu, A. E; Balsak, D; Deveci, E; Yavuz, D; Togrul, C; Karaman, E.
  • Ekinci, C; Dicle University. School of Medicine. Department of Histology and Embryology. Diyarbakir. TR
  • Tahaoglu, A. E; Dicle University. School of Medicine. Department of Histology and Embryology. Diyarbakir. TR
  • Balsak, D; Dicle University. School of Medicine. Department of Histology and Embryology. Diyarbakir. TR
  • Deveci, E; Dicle University. School of Medicine. Department of Histology and Embryology. Diyarbakir. TR
  • Yavuz, D; Dicle University. School of Medicine. Department of Obstetrics and Diseases. Diyarbakir. TR
  • Togrul, C; Dicle University. School of Medicine. Department of Histology and Embryology. Diyarbakir. TR
  • Karaman, E; Dicle University. School of Medicine. Department of Histology and Embryology. Diyarbakir. TR
Int. j. morphol ; 33(2): 607-610, jun. 2015. ilus
Article in English | LILACS | ID: lil-755517
ABSTRACT
This study aimed to assess association between preeclampsia with trophoblast cells and serum level of b-human chorionic gonadotropin (ß-hCG). Were compared 20 patients with preeclampsia and 20 control patients with respect to demographics, hematological parameters and the presence of trophopblast in placental samples. Patchy necrosis with loss of microvilli and gross thinning of the syncytium with distorted microvilli were seen in terminal villi of placentae of women with pre-eclampsia Syncytial cells at the molecular level crossings, especially at the level of ßhCG in conjunction with the changes in the preeclampsia was made on the histopathological changes to clarify the villi.
RESUMEN
El objetivo fue evaluar la asociación entre la preeclampsia con células trofoblásticas y concentración sérica de la gonadotropina coriónica humana b (ß-hCG). Se compararon 20 pacientes con preeclampsia y 20 pacientes de control con respecto a datos demográficos, parámetros hematológicos y la presencia de trofoblasto en muestras de placenta. Se observaron áreas dispersadas de necrosis, con pérdida de microvellosidades y adelgazamiento del sincitio con microvellosidades distorsionadas en las vellosidades terminales de placentas en mujeres con células sincitiales preeclámticas a nivel molecular, junto a altos niveles de ßhCG asociados a los cambios generados por la preeclampsia sobre los parámetros histopatológicos.
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Full text: Available Index: LILACS (Americas) Main subject: Pre-Eclampsia / Trophoblasts / Chorionic Gonadotropin, beta Subunit, Human Limits: Female / Humans / Pregnancy Language: English Journal: Int. j. morphol Journal subject: Anatomy Year: 2015 Type: Article Affiliation country: Turkey Institution/Affiliation country: Dicle University/TR

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Full text: Available Index: LILACS (Americas) Main subject: Pre-Eclampsia / Trophoblasts / Chorionic Gonadotropin, beta Subunit, Human Limits: Female / Humans / Pregnancy Language: English Journal: Int. j. morphol Journal subject: Anatomy Year: 2015 Type: Article Affiliation country: Turkey Institution/Affiliation country: Dicle University/TR