Serious stomatitis and esophagitis: a peculiar mucous reaction induced by pegylated liposomal doxorubicin
An. bras. dermatol
;
90(3,supl.1): 209-211, May-June 2015. ilus
Article
in English
| LILACS
| ID: lil-755740
ABSTRACT
Pegylated liposomal doxorubicin is an important antineoplastic agent with activity in a variety of solid tumors. It has a totally different profile of pharmacokinetics and toxicity compared with doxorubicin. It rarely causes side-effects like cardiotoxicity or hair loss, but frequently results in many kinds of mucocutaneous reactions, including palmar-plantar erythrodysesthesia, diffuse follicular rash, intertrigo-like eruption, new formation of melanotic macules, stomatitis and radiation recall dermatitis. We present a rare case of multiple myeloma who immediately developed serious stomatitis and esophatitis associated with minor palmar-plantar erythrodysesthesia after a single course of pegylated liposomal doxorubicin.
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Full text:
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Index:
LILACS (Americas)
Main subject:
Stomatitis
/
Doxorubicin
/
Esophagitis
/
Hand-Foot Syndrome
/
Antibiotics, Antineoplastic
Limits:
Aged
/
Female
/
Humans
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2015
Type:
Article
Affiliation country:
China
Institution/Affiliation country:
Sun Yat-sen University/CN
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