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Effects of penicillin and erythromycin on adherence of invasive and noninvasive isolates of Streptococcus pyogenes to laminin
Šmitran, Aleksandra; Vuković, Dragana; Gajić, Ina; Marinković, Jelena; Ranin, Lazar.
  • Šmitran, Aleksandra; University of Banja Luka. Faculty of Medicine. Department of Microbiology and Immunology. Banja Luka. BA
  • Vuković, Dragana; University of Banja Luka. Faculty of Medicine. Department of Microbiology and Immunology. Banja Luka. BA
  • Gajić, Ina; University of Banja Luka. Faculty of Medicine. Department of Microbiology and Immunology. Banja Luka. BA
  • Marinković, Jelena; University of Banja Luka. Faculty of Medicine. Department of Microbiology and Immunology. Banja Luka. BA
  • Ranin, Lazar; University of Banja Luka. Faculty of Medicine. Department of Microbiology and Immunology. Banja Luka. BA
Mem. Inst. Oswaldo Cruz ; 110(5): 684-686, Aug. 2015. tab
Article in English | LILACS | ID: lil-755893
ABSTRACT

This study investigated the possible relationship between the invasiveness of group A Streptococcus (GAS) strains and their abilities to adhere to laminin and assessed the effects of subinhibitory concentrations of penicillin and erythromycin on the ability of GAS to adhere to laminin. The adherence of noninvasive and highly invasive isolates of GAS to laminin was significantly higher than the adherence displayed by isolates of low invasiveness. Antibiotic treatment caused significant reductions in adherence to laminin in all three groups of strains. Penicillin was more successful in reducing the adherence abilities of the tested GAS strains than erythromycin.

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Full text: Available Index: LILACS (Americas) Main subject: Penicillins / Streptococcus pyogenes / Bacterial Adhesion / Erythromycin / Laminin / Anti-Bacterial Agents Limits: Humans Language: English Journal: Mem. Inst. Oswaldo Cruz Journal subject: Tropical Medicine / Parasitology Year: 2015 Type: Article / Project document Affiliation country: Bosnia and Herzegovina Institution/Affiliation country: University of Banja Luka/BA

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Full text: Available Index: LILACS (Americas) Main subject: Penicillins / Streptococcus pyogenes / Bacterial Adhesion / Erythromycin / Laminin / Anti-Bacterial Agents Limits: Humans Language: English Journal: Mem. Inst. Oswaldo Cruz Journal subject: Tropical Medicine / Parasitology Year: 2015 Type: Article / Project document Affiliation country: Bosnia and Herzegovina Institution/Affiliation country: University of Banja Luka/BA