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Corneal melanosis successfully treated using topical mitomycin-C and alcohol corneal epitheliectomy: a 3-year follow-up case report / Tratamento com êxito da melanose de córnea utilizando mitomicina-C tópica e epiteliectomia auxiliada por álcool: relato de caso com três anos de seguimento
Balcı, Mehmet; Yağcı, Ramazan; Güler, Emre; Haltaş, Hacer; Duman, Rahmi; Hepşen, İbrahim F..
  • Balcı, Mehmet; Abdurrahman Yurtaslan Oncology Training and Research Hospital. Department of Ophthalmology. Ankara. TR
  • Yağcı, Ramazan; Abdurrahman Yurtaslan Oncology Training and Research Hospital. Department of Ophthalmology. Ankara. TR
  • Güler, Emre; Abdurrahman Yurtaslan Oncology Training and Research Hospital. Department of Ophthalmology. Ankara. TR
  • Haltaş, Hacer; Abdurrahman Yurtaslan Oncology Training and Research Hospital. Department of Ophthalmology. Ankara. TR
  • Duman, Rahmi; Abdurrahman Yurtaslan Oncology Training and Research Hospital. Department of Ophthalmology. Ankara. TR
  • Hepşen, İbrahim F.; Abdurrahman Yurtaslan Oncology Training and Research Hospital. Department of Ophthalmology. Ankara. TR
Arq. bras. oftalmol ; 78(4): 255-256, July-Aug. 2015. ilus
Article in English | LILACS | ID: lil-759263
ABSTRACT
ABSTRACTWe report a case of primary acquired corneal melanosis without atypia associated with corneal haze in a patient with a history of limbal malignant melanoma and the effect of mitomycin-C. A 75-year-old woman with a history of limbal malignant melanoma presented with loss of vision in right eye. Corneal examination showed a patchy melanotic pigmentation with a central haze. Topical mitomycin-C improved visual acuity and corneal haze. However, the pigmented lesions persisted, and they were removed with alcohol corneal epitheliectomy. Histopathological examination demonstrated primary acquired melanosis without atypia. The lesions were successfully removed, and there were no recurrences during the follow-up period of 36 months. The association of conjunctival and corneal melanosis without atypia is a rare condition. In addition, co-existence of central corneal haze and melanosis may decrease visual acuity. Topical mitomycin-C and alcohol corneal epitheliectomy can be useful treatments in this condition.
RESUMO
RESUMORelatar um caso de melanose adquirida primária de córnea sem atipia, associado a haze corneano em um paciente com história de melanoma maligno de limbo e o efeito da mitomicina-C. Uma mulher de 75 anos de idade, com história de melanoma maligno do limbo apresentado com diminuição de visão no olho direito. O exame de córnea mostrou uma pigmentação melânica irregular com um haze central. O uso de mitomicina-C tópica levou à melhora da acuidade visual e da opacidade corneana. No entanto, as lesões pigmentadas persistiram e foram removidas com epiteliectomia associada ao álcool. O exame histopatológico demonstrou melanose adquirida primária sem atipia. As lesões foram removidas com êxito, e não houve recidiva durante o período de acompanhamento de 36 meses. A associação melanose sem atipia da conjuntiva e da córnea é uma condição rara. Além disso, a coexistência de haze corneano central e melanose pode diminuir a acuidade visual. O uso de mitomicina-C tópica e epiteliectomia corneana auxiliada pelo álcool podem ser tratamentos úteis nessa situação.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Mitomycin / Corneal Diseases / Melanosis / Antibiotics, Antineoplastic Type of study: Etiology study / Observational study / Prognostic study / Risk factors Limits: Aged / Female / Humans Language: English Journal: Arq. bras. oftalmol Journal subject: Ophthalmology Year: 2015 Type: Article Affiliation country: Turkey Institution/Affiliation country: Abdurrahman Yurtaslan Oncology Training and Research Hospital/TR

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Full text: Available Index: LILACS (Americas) Main subject: Mitomycin / Corneal Diseases / Melanosis / Antibiotics, Antineoplastic Type of study: Etiology study / Observational study / Prognostic study / Risk factors Limits: Aged / Female / Humans Language: English Journal: Arq. bras. oftalmol Journal subject: Ophthalmology Year: 2015 Type: Article Affiliation country: Turkey Institution/Affiliation country: Abdurrahman Yurtaslan Oncology Training and Research Hospital/TR