Interval and continuous exercise enhances aerobic capacity and hemodynamic function in CHF rats
Braz. j. phys. ther. (Impr.)
;
19(4): 257-263, July-Aug. 2015. tab, ilus
Article
in English
| LILACS
| ID: lil-761612
ABSTRACT
OBJECTIVE:
The aim of the present study was to compare the effects of continuous versus interval aerobic exercise training on hemodynamic parameters, cardiac remodeling, and maximal exercise capacity (MEC) in chronic heart failure (CHF) rats.METHOD:
Twenty-four male Wistar rats were subjected to myocardial infarction (MI) surgery. Five weeks post MI, the animals were assigned to one of three groups sedentary group (CHF-Sed, n=8), aerobic continuous training group (CHF-ACT, n=8), and aerobic interval training group (CHF-AIT, n=8). Treadmill training was performed five times a week for 8 weeks (ACT 50 min/day at 15 m/min and AIT 40 min/day with 8 min of warm-up at 10 m/min and exercise at 15 m/min 4×4 min interspersed with 4×4 min at 23 m/min). MEC was evaluated pre and post exercise program.RESULTS:
Left ventricular end-diastolic pressure (LVEDP), left ventricular mass/body mass ratio (LVMBM), and total collagen volume fraction were lower in the trained groups compared with the sedentary group, but no difference was found between the trained groups. Systolic ventricular pressure (SVP) and maximum positive derivative of LV pressure (+dP/dtmax) were higher in the trained groups, but CHF-ACT showed higher +dP/dtmax compared to CHF-AIT. Both training regimens were able to increase MEC. However, the aerobic interval training was superior for improving MEC.CONCLUSION:
Aerobic training is an important intervention to improve cardiac function and remodeling and physical capacity in CHF rats. Interval training is a potential strategy to maximize the results, but exercise type and intensity are still topics to be explored.
Full text:
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Index:
LILACS (Americas)
Main subject:
Blood Pressure
/
Exercise Therapy
/
Heart
/
Heart Failure
/
Hemodynamics
Limits:
Animals
Language:
English
Journal:
Braz. j. phys. ther. (Impr.)
Journal subject:
MEDICINA FISICA E REABILITACAO
Year:
2015
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal de Ciências da Saúde de Porto Alegre/BR
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