Evolución alejada en portadoras asintomáticos HBsAg(PA-HBsAg) en un área de baja prevalencia de hepatocarcinoma
Acta gastroenterol. latinoam
;
19(1): 21-30, jan.-mar. 1989. tab
Article
in Spanish
| LILACS
| ID: lil-76189
RESUMO
Data provided by 51 voluntaru blood donnors identified as asymptomatic HBsAg carriers five to ten years (x = 7.5 years) before their inclusion in the study are analysed towards their long-term evolution. HBsAg clearance was estimated 2.5% yearly and 83.9% of those remaining positive showed the classical non-replicative serological pattern,; another 12.9% were negative for both HBeAg - Anti HBe (serovonversion window?), one of them presenting raised ASATALAT levels and enhanced histological activity (lobular chronic hepatitis). Neither alpha-fetoprotein seric levels (RIA) nor liver ultrasonography demonstrated hepato cellular carcinoma suspicion signs in 35 HBsAg positive cases to this methods; ASAT-ALAT levels raised over two fold the normal superior limit ion only 11.4%, and neither agressive chronic liver disease nor hepatocyte dissplasia was showed in 17 biopsed cases (70.6% normal; 23.6% chronic reactive or chronic persistent hepatitis; 5.8% chronic liobular hepatitis). One out of five patients biopsed with a seven years interval showed histologic worsening
Search on Google
Index:
LILACS (Americas)
Main subject:
Hepatitis B virus
/
Carcinoma, Hepatocellular
/
Hepatitis B
/
Hepatitis B Surface Antigens
/
Liver Neoplasms
Type of study:
Prevalence study
/
Risk factors
/
Screening study
Limits:
Humans
Language:
Spanish
Journal:
Acta gastroenterol. latinoam
Journal subject:
Gastroenterology
Year:
1989
Type:
Article
Similar
MEDLINE
...
LILACS
LIS