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Optical coherence tomography imaging of the basal ganglia: feasibility and brief review
Lopez, W. O. Contreras; Ângelos, J. S.; Martinez, R. C. R.; Takimura, C. K.; Teixeira, M. J.; Lemos Neto, P. A.; Fonoff, E. T..
Affiliation
  • Lopez, W. O. Contreras; Universidade de São Paulo. Faculdade de Medicina. Departamento de Neurologia. São Paulo. BR
  • Ângelos, J. S.; Universidade de São Paulo. Faculdade de Medicina. Departamento de Neurologia. São Paulo. BR
  • Martinez, R. C. R.; Universidade de São Paulo. Faculdade de Medicina. Departamento de Neurologia. São Paulo. BR
  • Takimura, C. K.; Universidade de São Paulo. Faculdade de Medicina. Departamento de Neurologia. São Paulo. BR
  • Teixeira, M. J.; Universidade de São Paulo. Faculdade de Medicina. Departamento de Neurologia. São Paulo. BR
  • Lemos Neto, P. A.; Universidade de São Paulo. Faculdade de Medicina. Departamento de Neurologia. São Paulo. BR
  • Fonoff, E. T.; Universidade de São Paulo. Faculdade de Medicina. Departamento de Neurologia. São Paulo. BR
Rev. bras. pesqui. méd. biol ; Braz. j. med. biol. res;48(12): 1156-1159, Dec. 2015. graf
Article in En | LILACS | ID: lil-762922
Responsible library: BR1.1
ABSTRACT
Optical coherence tomography (OCT) is a promising medical imaging technique that uses light to capture real-time cross-sectional images from biological tissues in micrometer resolution. Commercially available optical coherence tomography systems are employed in diverse applications, including art conservation and diagnostic medicine, notably in cardiology and ophthalmology. Application of this technology in the brain may enable distinction between white matter and gray matter, and obtainment of detailed images from within the encephalon. We present, herein, the in vivo implementation of OCT imaging in the rat brain striatum. For this, two male 60-day-old rats (Rattus norvegicus, Albinus variation, Wistar) were stereotactically implanted with guide cannulas into the striatum to guide a 2.7-French diameter high-definition OCT imaging catheter (Dragonfly™, St. Jude Medical, USA). Obtained images were compared with corresponding histologically stained sections to collect imaging samples. A brief analysis of OCT technology and its current applications is also reported, as well as intra-cerebral OCT feasibility on brain mapping during neurosurgical procedures.
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Full text: 1 Index: LILACS Main subject: Basal Ganglia / Diagnosis, Computer-Assisted / Tomography, Optical Coherence Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Braz. j. med. biol. res / Rev. bras. pesqui. méd. biol Journal subject: BIOLOGIA / MEDICINA Year: 2015 Type: Article / Project document

Full text: 1 Index: LILACS Main subject: Basal Ganglia / Diagnosis, Computer-Assisted / Tomography, Optical Coherence Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Braz. j. med. biol. res / Rev. bras. pesqui. méd. biol Journal subject: BIOLOGIA / MEDICINA Year: 2015 Type: Article / Project document