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Colangiopancreatografía retrograda endoscópica (CPRE) precoz y pancreatitis aguda biliar (PAB) / Early endoscopic retrograde cholangiopancreatography (ERCP) and acute biliary pancreatitis (ABP)
Ovalle A., Loreto.
  • Ovalle A., Loreto; Hospital San Juan de Dios. Unidad de Gastroenterología. Santiago. CL
Gastroenterol. latinoam ; 24(supl.1): S95-S97, 2013.
Article in Spanish | LILACS | ID: lil-763733
ABSTRACT
For over 20 years we have discussed the indication of early endoscopic retrograde cholangiopancreatography (ERCP) (72 h before the onset of symptoms) in acute biliary pancreatitis (ABP), seeking to stop the inflammatory process, reducing complications and mortality, taking into account that ERCP can cause pancreatitis and other complications such as perforation and hemorrhage. To elucidate this problem, there have been multiple meta-analyses based on the same 3 or 5 randomized controlled trials of early ERCP versus conventional treatment (including elective ERCP) in ABP, which have produced conflicting results. There is agreement regarding that it is not indicated in mild ABP, and it is indicated in ABP associated with cholangitis and persistent obstruction of the ampulla of Vater. There is controversy in severe presentation of ABP, since current evidence does not definitely show the usefulness of early ERCP. No more complications related to ERCP have been reported in this situation.
RESUMEN
Desde hace más de 20 años se discute la indicación de la colangiopancreatografía retrógrada endoscópica (CPRE) precoz (antes de 72 h del inicio de los síntomas) en la pancreatitis aguda biliar (PAB), buscando detener el proceso inflamatorio, disminuyendo sus complicaciones y su mortalidad, tomando en cuenta que la CPRE puede ser causa de pancreatitis y otras complicaciones como perforación y hemorragia. Para dilucidar este problema se han realizado múltiples meta-análisis basados en los mismos 3 ó 5 estudios aleatorizados y controlados de CPRE precoz versus el tratamiento convencional (que incluye CPRE electiva) en PAB, los cuales han dado resultados discordantes. En lo que hay acuerdo es en que no está indicada en la PAB leve y sí está indicada en la PAB asociada a colangitis y a obstrucción persistente de la ampolla de Vater. En la PAB de presentación grave hay controversia; la evidencia actual no demuestra en forma definitiva la utilidad de una CPRE precoz. No se ha reportado mayor número de complicaciones relacionadas a la CPRE en esta situación.
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Full text: Available Index: LILACS (Americas) Main subject: Pancreatitis / Biliary Tract Diseases / Cholangiopancreatography, Endoscopic Retrograde Type of study: Controlled clinical trial / Diagnostic study / Screening study Limits: Humans Language: Spanish Journal: Gastroenterol. latinoam Journal subject: Gastroenterology Year: 2013 Type: Article Affiliation country: Chile Institution/Affiliation country: Hospital San Juan de Dios/CL

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Full text: Available Index: LILACS (Americas) Main subject: Pancreatitis / Biliary Tract Diseases / Cholangiopancreatography, Endoscopic Retrograde Type of study: Controlled clinical trial / Diagnostic study / Screening study Limits: Humans Language: Spanish Journal: Gastroenterol. latinoam Journal subject: Gastroenterology Year: 2013 Type: Article Affiliation country: Chile Institution/Affiliation country: Hospital San Juan de Dios/CL