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Effects of nitrofurazone on correction of abdominal wall defect treated with polypropylene mesh involved by fibrous tissue
Yasojima, Edson Yuzur; Ribeiro Júnior, Rubens Fernando Gonçalves; Pessôa, Thyago Cezar Prado; Cavalcante, Lainy Carollyne da Costa; Ramos, Suzana Rodrigues; Serruya, Yuri Aarão Amaral; Moraes, Mateus Malta de.
  • Yasojima, Edson Yuzur; Universidade Estadual do Pará. Department of General Surgery. Belem. BR
  • Ribeiro Júnior, Rubens Fernando Gonçalves; Universidade Estadual do Pará. Department of General Surgery. Belem. BR
  • Pessôa, Thyago Cezar Prado; Universidade Estadual do Pará. Department of General Surgery. Belem. BR
  • Cavalcante, Lainy Carollyne da Costa; Universidade Estadual do Pará. Department of General Surgery. Belem. BR
  • Ramos, Suzana Rodrigues; Universidade Estadual do Pará. Department of General Surgery. Belem. BR
  • Serruya, Yuri Aarão Amaral; Universidade Estadual do Pará. Department of General Surgery. Belem. BR
  • Moraes, Mateus Malta de; Universidade Estadual do Pará. Department of General Surgery. Belem. BR
Acta cir. bras ; 30(10): 686-690, tab, graf
Article in English | LILACS | ID: lil-764397
ABSTRACT

PURPOSE:

Toevaluate the effects of nitrofurazone on the correction of abdominal wall defect treated with polypropylene mesh involved by fibrous tissue in rats.

METHODS:

A defect in the abdominal wall was created and corrected with polypropylene mesh in 20 rats. They were randomly distributed into four groups control, fibrous mesh, nitrofurazone and nitrofurazone dip in the mesh. Euthanasia was performed in 21 post-operative days. The healing process was analyzed regarding the meshes and macroscopic and microscopic aspects.

RESULTS:

All animals had adhesions. However, no statistically significant difference (p>0.05) when compared between groups. Similarly microscopic analysis, in which there was no statistical significance level for the evaluated parameters such as mono and polymorphonuclear lymphocytes, granuloma, fibrosis, necrosis and collagen proliferation.

CONCLUSION:

There was no significant effect on the abdominal wall defect repair with polypropylene mesh surrounded by fibrous tissue when dipped in nitrofurazone 2%.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Polypropylenes / Surgical Mesh / Abdominal Wall / Anti-Infective Agents / Nitrofurazone Type of study: Evaluation studies Limits: Animals Language: English Journal: Acta cir. bras Journal subject: General Surgery / Procedimentos Cir£rgicos Operat¢rios Year: 2015 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Estadual do Pará/BR

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Full text: Available Index: LILACS (Americas) Main subject: Polypropylenes / Surgical Mesh / Abdominal Wall / Anti-Infective Agents / Nitrofurazone Type of study: Evaluation studies Limits: Animals Language: English Journal: Acta cir. bras Journal subject: General Surgery / Procedimentos Cir£rgicos Operat¢rios Year: 2015 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Estadual do Pará/BR